Products Indometacin has been approved in many countries since 1999 in the form of eye drops (Indophtal, Indophtal UD). Structure and properties Indomethacin (C19H16ClNO4, Mr = 357.8 g/mol) is an indoleacetic acid derivative. It exists as a white to yellow crystalline powder that is practically insoluble in water. Effects Indomethacin (ATC S01BC01) has analgesic and … Indomethacin Eye Drops
Products Copper sulfate is available as a pure substance in pharmacies and drugstores. It is also found as an active ingredient in medicines, for example in copper zinc solution (Eau d’Alibour). Structure and properties Copper(II) sulfate (CuSO4, Mr = 159.6 g/mol) is a copper salt of sulfuric acid. In pharmacy as often used copper sulfate … Copper Sulfate
Products Aminolevulinic acid is commercially available as patches and gels (Alacare, Ameluz). Structure and properties The 5-aminolevulinic acid (C5H9NO3, Mr = 131.1 g/mol) is a nonproteinogenic amino acid. It exists in the drug as a hydrochloride, a white crystalline solid that is soluble in water. Effects 5-Aminolevulinic acid (ATC L01XD04) is phototoxic and causes destruction … 5-Aminolevulinic Acid
Products Neuraminidase inhibitors are commercially available in the form of capsules, powder for oral suspension, powder inhalers, and injectables. The first agents to be approved were zanamivir (Relenza) in 1999, followed by oseltamivir (Tamiflu). Laninamivir (Inavir) was released in Japan in 2010 and Peramivir (Rapivab) in the USA in 2014. The public is most familiar … Neuraminidase Inhibitor
Products Paritaprevir was approved in many countries in 2014 in film-coated tablet form (Viekirax, combination drug). Effects Paritaprevir has antiviral properties against HCV. The effects are due to binding to the NS3/4A protease complex. HCV NS3 serine protease is an enzyme involved in viral replication. To increase availability and allow once-daily administration, paritaprevir is combined … Paritaprevir
Products Paromomycin is commercially available in the form of capsules (Humatin). It has been approved in many countries since 1961. Indications Precoma (clouding of consciousness preceding coma) and coma hepaticum (hepatic coma). Prophylaxis of hepatogenic encephalopathies. Reduction of intestinal flora before surgery Taeniasis (tapeworm) Intestinal amoebiasis
Effects Fusion inhibitors have antiviral properties against viruses. They inhibit fusion with the host cell and prevent virus entry. Indications For the treatment of viral infectious diseases. Active ingredients Enfuvirtide (Fuzeon) Umifenovir (Arbidol)
Products Heberprot-P is a Cuban drug developed in Havana am and has been on the market since 2007. It is now available as an injectable in numerous countries. It is not currently registered in many countries. Structure and properties Heberprot-P contains recombinant human epidermal growth factor (rhEGF), a comparatively small protein with 53 amino acids … Siphonprot-P
Products Memantine is commercially available as film-coated tablets, meltable tablets, and oral solution (Axura, Ebixa). It has been approved in many countries since 2003. Generic versions were registered in 2014. Structure and properties Memantine (C12H21N, Mr = 179.3 g/mol) is present in drugs as memantine hydrochloride, a white powder that is insoluble in water. Memantine … Memantine
Products APN01 is in clinical development at Apeiron Biologics. Structure and properties APN01 is a recombinant, soluble, and human angiotensin-converting enzyme 2 (ACE2). Effects APN01 functions as a false receptor for the coronavirus SARS-CoV-2, the causative agent of the viral disease Covid-19. SARS-CoV-2 uses ACE2 for attachment and entry into host cells. APN01 is a … APN01 (Recombinant ACE2)
Products Lysine acetyl salicylate is commercially available as powder and injectable (Aspégic, Alcacyl powder, Germany: e.g., Aspirin i.v., Aspisol). It has been approved in many countries since 1973. Migpriv, which is combined with metoclopramide for migraine, was withdrawn from the market in many countries in December 2011 see under Migpriv. Kardégic was withdrawn from the … Lysine Acetyl Salicylate
Products Thiopental is commercially available as an injectable (generic). It has been approved in many countries since 1947. Structure and properties Thiopental (C11H18N2O2S, Mr = 242.3 g/mol) is present in the drug as thiopental sodium, a yellowish white, hygroscopic powder that is readily soluble in water. It is a lipophilic thiobarbiturate identical to pentobarbital except … Thiopental
