Products Atezolizumab was approved as an infusion product in the United States in 2016 and in the EU and many countries in 2017 (Tecentriq). Structure and properties Atezolizumab is a humanized IgG1κ monoclonal antibody with a molecular mass of 145 kDa. Effects Atezolizumab (ATC L01XC32) has immunostimulatory and antitumor properties. The effects are due to … Atezolizumab
Products Opipramol is commercially available in the form of dragées (Insidon). It has been approved in many countries since 1961, originally by Geigy, later by Novartis. Structure and properties Opipramol (C23H29N3O, Mr = 363.5 g/mol) structurally belongs to the tricyclic antidepressants and is a dibenzazepine derivative. It is present in the drug as opipramol dihydrochloride. … Opipramol
Products Maropitant is commercially available as a solution for injection and in tablet form as a veterinary drug (Cerenia). It has been approved in many countries since 2008. Structure and properties Maropitant (C38H50N2O9, Mr = 678.8 g/mol) Effects Maropitant (ATCvet QA04AD90) has antiemetic properties. The effects are due to inhibition of substance P binding to … Maropitant
Products Sirolimus (rapamycin) is commercially available as coated tablets and as an oral solution (Rapamune). It has been approved in many countries since 2000. Structure and properties Sirolimus (C51H79NO13, Mr = 914.2 g/mol) is a large, lipophilic and complex molecule. It is a macrocyclic lactone extracted from. This fungus was originally identified in a soil … Sirolimus (Rapamycin)
Products Pomalidomide is commercially available in the form of hard capsules (Imnovid). It has been approved in many countries since 2014. It has been registered in the EU and the United States since 2013. Structure and properties Pomalidomide (C13H11N3O4, Mr = 273.2 g/mol) is an amino derivative of thalidomide and a racemate. It is also … Pomalidomide
Products Oxymetazoline cream was approved in the United States in 2017 (Rhofade, 1%). Oxymetazoline is also available as a nasal spray at a lower concentration (Nasivin); see Oxymetazoline. Structure and properties Oxymetazoline (C16H24N2O, Mr = 260.4 g/mol) is present in drugs as oxymetazoline hydrochloride, a white crystalline powder that is readily soluble in water. It … Oxymetazoline Cream
