Products Thiostrepton is marketed as a lotion in combination with other active ingredients. It has been approved in many countries since 1973. Effects Thiostrepton (ATCvet QD07CB01) has antibacterial properties effective against Gram-positive and Gram-negative pathogens of skin infections. Indications Skin diseases (veterinary drug).
Products Green coffee is commercially available in many countries in the form of capsules, powder and toffees from various suppliers, among others. Ingredients Green coffee is made from raw and unroasted coffee beans. The powder or extracts are used. The effects are primarily attributed to the high content of chlorogenic acids. According to some sources, … Green Coffee
Definition So-called “creeping in” is a gradual increase in the dose of a drug over days or a few weeks. This is used to slowly accustom the patient to the drug and to test individual tolerability. Creeping in helps to avoid undesirable effects. The target dose may be predefined or determined individually. In the second … Gradual Increase of the Dose of a Drug
Products For ALS treatment, edaravone was approved in Japan in 2015 (Radicut) and in the United States in 2017 as an infusion product (Radicava). In the EU, edaravone has orphan drug status. In many countries, the drug has been registered since 2019. Structure and properties Edaravone (C10H10N2O, Mr = 174.2 g/mol) is a substituted 2-pyrazolin-5-one. … Edaravon
Products Eluxadoline was approved in the form of film-coated tablets in the US in 2015, in the EU in 2016, and in many countries in 2018 (US: Viberzi, EU, CH: Truberzi). Structure and properties Eluxadoline (C32H35N5O5, Mr = 569.7 g/mol) Effects Eluxadoline (ATC A07DA06) has antidiarrheal and analgesic properties. It is an agonist at μ-opioid … Eluxadoline
Products Prednicarbate is commercially available as a cream, solution, and ointment (Prednitop, Prednicutan). It has been approved in many countries since 1990. Structure and properties Prednicarbate (C27H36O8, Mr = 488.6 g/mol) belongs to the class of potent glucocorticoids (class III). It is a non-halogenated prednisolone derivative. It exists as an odorless, white to yellowish-white, crystalline … Prednicarbate
Products Encorafenib was approved in capsule form in the United States and EU in 2018 and in many countries in 2019 (Braftovi). Structure and properties Encorafenib (C22H27ClFN7O4S, Mr = 540.0 g/mol) exists as a white powder that is somewhat soluble in water only at low pH. Effects Encorafenib (ATC L01XE46) has antitumor and antiproliferative properties. … Encorafenib
Products Antipyretics are available in numerous dosage forms. These include, for example, tablets, effervescent tablets, suppositories, juices, and chewable tablets. The name is derived from the technical term pyrexia (fever). The first synthetic agents, such as acetanilide, salicylic acid, and acetylsalicylic acid, were developed in the 19th century. Structure and properties Antipyretics do not have … Antipyretics
Products Pertuzumab is commercially available as a concentrate for the preparation of an infusion solution (Perjeta). It was approved in many countries in 2012. Structure and properties Pertuzumab is a recombinant humanized IgG1 monoclonal antibody. It was developed as a successor to trastuzumab (Herceptin). Effects Pertuzumab (ATC L01XC13) has cytostatic and antiproliferative properties. The effects … Pertuzumab
Products The cannabis oral spray Sativex was approved in many countries in 2013. It is subject to narcotics legislation and requires an enhanced prescription. In Germany, Sativex has been available since 2011. Structure and properties The oral spray contains a thick extract of the hemp plant L., which is extracted from the leaves and flowers … Cannabis Mouth Spray
Products Cortisone mixed ointments are not commercially available as finished drug products. They are prepared in pharmacies as extemporaneous preparations. Usually, a cream or ointment containing cortisone is diluted by mixing it with an ingredient-free base, such as Excipial or Antidry. The concentration of the glucocorticoid decreases in the process. However, the risk for adverse … Cortisone Mixed Ointments
Products Torasemide is commercially available in tablet form (Torem, generic). It has been approved in many countries since 1993. Structure and properties Torasemide (C16H20N4O3S, Mr = 348.4 g/mol) exists as a white powder that is practically insoluble in water. It is a pyridine-sulfonylurea derivative. Torasemide differs structurally from its precursor furosemide (Lasix, generics), a sulfonamide. … Torasemide
