Night Work

Background According to the Labor Law, shift work refers to employees working staggered and alternately at the same workplace: “Shift work occurs when two or more groups of employees are assigned to work staggered and alternately at the same workplace according to a specific schedule.” This definition also refers to work during the day. From … Night Work

Attention Deficit Hyperactivity Disorder

Symptoms Attention deficit hyperactivity disorder (ADHD, ADHD) is a developmental disorder of the central nervous system. Leading symptoms include: Inattention, decreased ability to concentrate. Hyperactivity, motor restlessness, restlessness. Impulsive (thoughtless) behavior Emotional problems Although ADHD begins in childhood, it also affects adolescents and adults and is more common in boys than girls. It presents itself, … Attention Deficit Hyperactivity Disorder

Amphetamine

Products In many countries, no drugs containing amphetamine are currently registered. The active ingredient is subject to narcotics legislation and requires an aggravated prescription, but is basically not prohibited like other substances from the amphetamine group. In some countries, medicines containing dexamphetamine are on the market, for example in Germany and the USA. Structure and … Amphetamine

Amphetamines

Products Amphetamines are commercially available as drugs in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. Structure and properties Amphetamines are derivatives of amphetamine. It is a methylphenethylamine structurally related to endogenous monoamines and stress hormones epinephrine and norepinephrine. Amphetamines are racemates and the –enantiomers. Effects Amphetamines have sympathomimetic, central stimulant, bronchodilator, psychoactive, … Amphetamines

Dexmethylphenidate

Products Dexmethylphenidate is commercially available in the form of capsules with a modified release of active ingredient (Focalin XR). It was approved in many countries in 2009. Since it does not contain L-threo-methylphenidate, the strengths are correspondingly half less (5 mg, 10 mg, 15 mg, 20 mg) than Ritalin LA (10 mg, 20 mg, 30 … Dexmethylphenidate

Sibutramine

Products and withdrawal from the market Sibutramine was approved in 1999 and was commercially available in many countries in 10- and 15-mg capsule form (Reductil, Abbott AG). On March 29, 2010, Abbott AG, in consultation with Swissmedic, informed the public that the marketing authorization had been suspended. Since then, sibutramine may no longer be prescribed … Sibutramine

Narcotics Effects and Side Effects

Products The narcotics are a group of centrally acting drugs and substances, which are strongly regulated and controlled by the state respectively by the drug and health authorities. This is primarily to prevent abuse and to protect the population from the undesirable effects and addiction. Certain narcotics – for example, many potent hallucinogens – are … Narcotics Effects and Side Effects

Sympathomimetics

Products Sympathomimetics are commercially available, for example, in the form of tablets, capsules, granules, injectable solutions, eye drops, and nasal sprays. Structure and properties Sympathomimetics are structurally derived from the natural neurotransmitters epinephrine and norepinephrine. Effects Sympathomimetics have sympathomimetic properties, meaning that they promote the effects of the sympathetic nervous system, a portion of the … Sympathomimetics

Lisdexamphetamine

Products Lisdexamphetamine (LDX) was approved in many countries in March 2014 in capsule form (Elvanse). It has been available in the United States since 2007 (Vyvanse). The dosage form is non-retarded, unlike other ADHD medications. Continuous release is achieved with the conversion of the prodrug. Lisdexamphetamine is legally classified as a narcotic and therefore requires … Lisdexamphetamine

Transdermal Patches

Products Transdermal patches are approved as medicinal products. They offer themselves as an alternative to other modes of application such as peroral and parenteral administration. The first products were launched in the 1970s. Structure and properties Transdermal patches are flexible pharmaceutical preparations of varying sizes and thinness that contain one or more active ingredients. They … Transdermal Patches

Methylphenidate: Effects, Uses & Risks

Methylphenidate is chemically related to amphetamine and has a stimulant effect as a drug. It is also known by the trade name Ritalin. The drug is mainly used for the treatment of attention-deficit/hyperactivity disorder, known as ADHD, and narcolepsy. What is methylphenidate? The drug is mainly used for the treatment of ADHD. Like amphetamine, methylphenidate … Methylphenidate: Effects, Uses & Risks

Dasotralin

Products Sunovion’s dasotraline is in the regulatory phase and is therefore not yet available. Structure and properties Dasotralin (C16H15Cl2N, Mr = 292.2 g/mol) is a diastereomer of the desmethyl metabolite of sertraline (Zoloft, generics). Effects Dasotraline selectively inhibits the reuptake of the neurotransmitters dopamine and norepinephrine into presynaptic neurons in the central nervous system. The … Dasotralin