Products Lesinurad was approved in the US in 2015, in the EU in 2016, and in many countries in 2017 in film-coated tablet form (Zurampic). A fixed-dose combination with allopurinol was released in the US in 2017 (Duzallo), in the EU in 2018, and in many countries in 2019. Structure and properties Lesinurad (C17H14BrN3O2S, Mr … Lesinurad
Products Naftifine is commercially available as a gel and cream for external use. The drug has not yet been registered in many countries. Structure and properties Naftifine (C21H21N, Mr = 287.4 g/mol) is a lipophilic naphthalene derivative and belongs to the group of allylamines, which includes terbinafine. In pharmaceuticals, it is present as naftifine hydrochloride. … Naftifine
Products Butenafine is not commercially available in many countries. In other countries, it is available as a cream (e.g., Mentax) and other products. Structure and properties Butenafine (C23H27N, Mr = 317.5 g/mol) is present in drugs as butenafine hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a naphthalene derivative and … Butenafine
Products Terbinafine is commercially available in tablet form (Lamisil, generic). It has been approved in many countries since 1991. Structure and properties Terbinafine (C21H25N, Mr = 291.4 g/mol) is present in drugs as terbinafine hydrochloride, a white powder that is very sparingly soluble in water. It is an allylamine and naphthalene derivative. Effects Terbinafine (ATC … Terbinafine (Nail Fungus)
