Nicorandil

Products Nicorandil is commercially available in tablet form (Dancor). It has been approved in many countries since 1993. Structure and properties Nicorandil (C8H9N3O4, Mr = 211.2 g/mol), like nitroglycerin, is an organic nitrate. It is a combination of the vitamin nicotinamide with an ethyl nitrate. Effects Nicorandil (ATC C01DX16) has vasodilator, antihypertensive, and cardioprotective properties. … Nicorandil

Nitroglycerin Capsules

Products Nitroglycerin is commercially available in many countries in the form of chewable capsules (Nitroglycerin Streuli). The active ingredient was produced and used medicinally as early as the 19th century. Structure and properties Nitroglycerin or glycerol trinitrate (GTN, C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an … Nitroglycerin Capsules

Nitroglycerin Patch

Products Nitroglycerin has been approved in many countries since 1981 in the form of a transdermal patch (Nitroderm, others). Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an oily liquid and is explosive if not stabilized. Synthesis Effects Nitroglycerin (ATC … Nitroglycerin Patch

Isoket®

Active ingredient Isosorbiddinitrate (ISDN) Mode of action Isosorbide dinitrate belongs to the group of nitrates from which nitric oxide (NO) can be released after absorption into the body. Nitric oxide leads to dilation of blood vessels (vasodilation), especially of the veins and larger coronary arteries. Nitrates thus lead to a reduction in the so-called preload, … Isoket®

Contraindications | Isoket®

Contraindications Isosorbide dinitrate must not be used in cases of known hypersensitivity to the active substance, acute circulatory failure, cardiogenic shock, systolic blood pressure < 90 mmHg (hypotension), hypertrophic obstructive cardiomyopathy (HOCM), and narrowing of the mitral valve or aortic valve (stenosis). Interactions A combination of ISDN and drugs to treat erectile dysfunction from the … Contraindications | Isoket®

Miconazole

Products Miconazole is available as a cream, miconazole mouth gel and shampoo, and commercially (e.g., Daktarin). It has been approved in many countries since 1972. This article refers to external therapy. See also under miconazole mouth gel and miconazole for nail fungus. The nail tincture for nail fungus treatment is no longer marketed in many … Miconazole