Symptoms Anal fissure is a tear or cut in the skin of the anal canal. This results in severe pain that occurs during and up to several hours after defecation. It may radiate locally and be accompanied by an uncomfortable itching sensation. Fresh blood can often be seen on toilet paper or stool. Causes Possible … Anal Fissure: Symptoms, Diagnosis, Causes and Treatment
Products Nicorandil is commercially available in tablet form (Dancor). It has been approved in many countries since 1993. Structure and properties Nicorandil (C8H9N3O4, Mr = 211.2 g/mol), like nitroglycerin, is an organic nitrate. It is a combination of the vitamin nicotinamide with an ethyl nitrate. Effects Nicorandil (ATC C01DX16) has vasodilator, antihypertensive, and cardioprotective properties. … Nicorandil
Symptoms Diffuse esophageal spasm manifests as seizure-like pain behind the breastbone (chest pain) and difficulty swallowing. The pain may radiate to the arms and jaw, similar to angina. Other possible symptoms include shortness of breath, cramping and burning. The duration of attacks varies, ranging from seconds to minutes. They are often triggered by food intake, … Diffuse Esophageal Spasm
Products Nitrates are commercially available in the form of chewable capsules, transdermal patches, infusion preparations, ointment, sustained-release tablets, sustained-release capsules, and sprays. As the first representative, nitroglycerin was already produced in the 19th century and used for the treatment of angina pectoris. Nitrates are thus among the oldest synthetic drugs. Structure and properties Organic nitrates … Organic Nitrates
Products Uprima sublingual tablets (2 mg, 3 mg) for erectile dysfunction are no longer marketed in many countries. The marketing authorization was not renewed by Abbott AG in 2006. Commercial reasons were cited, probably attributed to competition from phosphodiesterase-5 inhibitors (e.g., sildenafil, Viagra). It is also possible that a post-marketing study had played a role, … Apomorphine
Symptoms The leading symptoms of stomach burning include an uncomfortable burning sensation behind the breastbone and acid regurgitation. The burning sensation occurs primarily after eating, and pain along the esophagus may radiate. Other accompanying symptoms include hoarseness, coughing, nausea, difficulty swallowing, sleep disturbances, respiratory problems, a foreign body sensation in the throat, and enamel changes. … Stomach Burn
Symptoms A heart attack manifests itself in acute and severe pain and a feeling of tightness and pressure in the chest, which may also radiate to the arms, jaw or abdomen. Other symptoms include nausea, indigestion, shortness of breath, coughing, a break of sweat, pallor, fear of death, unconsciousness and dizziness. A myocardial infarction lasts … Heart Attack Causes and Treatment
Products Nitroglycerin is commercially available in many countries in the form of chewable capsules (Nitroglycerin Streuli). The active ingredient was produced and used medicinally as early as the 19th century. Structure and properties Nitroglycerin or glycerol trinitrate (GTN, C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an … Nitroglycerin Capsules
Products Nitroglycerin has been approved in many countries since 1981 in the form of a transdermal patch (Nitroderm, others). Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an oily liquid and is explosive if not stabilized. Synthesis Effects Nitroglycerin (ATC … Nitroglycerin Patch
Products Rectogesic ointment is approved in many countries (some countries: Rectiv). Nitroglycerin ointments are also used in a higher concentration for transdermal treatment of angina (2%). This article refers to rectal administration for anal fissure. Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is nitrated glycerol. Pure nitroglycerin is explosive and … Nitroglycerin Ointment
Symptoms Low blood pressure does not necessarily cause symptoms and often remains asymptomatic. Possible symptoms include: Pale and cold skin, cold hands and feet, sweating. Visual disturbances: Blackening in front of the eyes, flickering, parts of the visual field fail Concentration disorders Rapid pulse, palpitations Ringing in the ears Dizziness Weakness, fatigue, lack of performance … Low Blood Pressure
Products Molsidomine is commercially available in the form of tablets and sustained-release tablets (Corvaton). The drug has been approved in many countries since 1980. Structure and properties Molsidomine (C9H14N4O4, Mr = 242.2 g/mol) is a prodrug that is biotransformed in the liver to the active metabolite linsidomine (SIN-1). It exists as a white crystalline powder … Molsidomin
