Symptoms Esophageal achalasia is a rare and chronic progressive motility disorder of the lower esophagus that manifests as dysphagia and retrosternal pain. Patients feel discomfort during and after eating. Possible accompanying symptoms include bad breath, cramping, and burning. Ingested food remains in the esophagus and cannot be adequately transported to the stomach. This can lead … Esophageal Achalasia
Products Tadalafil is commercially available in the form of film-coated tablets (Cialis, Adcirca, generics). It has been approved in many countries since 2004. Generics were registered in 2016 and came on the market in 2019. This article is related to erectile dysfunction treatment. Structure and properties Tadalafil (C22H19N3O4, Mr = 389.4 g/mol) exists as a … Tadalafil
Products Alfuzosin is commercially available in sustained-release tablet form and has been approved in many countries since 1994. In addition to the original Xatral, generic versions are also available. Structure and properties Alfuzosin (C19H27N5O4, Mr = 389.45 g/mol) is a quinazoline derivative. It is present in drugs as alfuzosin hydrochloride, a white crystalline powder that … Alfuzosin
Symptoms Medication-overuse headache, depending on the preexisting symptoms, manifests, for example, like a tension headache as bilateral, pressing pain, or like a migraine, unilateral, pulsating, and accompanied by nausea, vomiting, and sensitivity to light and noise. The pain occurs chronically for at least 15 days of the month, every other day or daily. When the … Medication Overuse Headache
Causes and classification 1. primary, idiopathic headache without underlying disease: Tension headache Migraine Cluster headache Mixed and other, rarer primary forms. 2. secondary headache: the causes of secondary headache as a result of a disease, a particular condition or substances are numerous: head or cervical trauma: Posttraumatic headache Cervical spine acceleration trauma Vascular disorders of … Headache
Products Isosorbide dinitrate is commercially available in many countries in the form of tablets, sustained-release tablets, sustained-release capsules, as an infusion concentrate, and as a spray (Isoket). The drug first came on the market in the 1940s. Structure and properties Isosorbide dinitrate (C6H8N2O8, Mr = 236.14 g/mol) exists as a white, fine, crystalline and odorless … Isosorbide Dinitrate
Products Isosorbide mononitrate was commercially available in the form of divisible extended-release tablets (Corangin). It was approved in many countries in 1987 and was withdrawn from the market in 2014. Other nitrates can be used as substitutes, such as isosorbide dinitrate. Structure and properties Isosorbide mononitrate (C6H9NO6, Mr = 191.1 g/mol) is an organic nitrate. … Isosorbide Mononitrate
Products Vardenafil is commercially available in the form of film-coated tablets and oral tablets (Levitra, co-marketing drug: Vivanza). It has been approved in many countries since 2003. Generic versions were approved in 2018. Structure and properties Vardenafil (C23H32N6O4S, Mr = 488.6 g/mol) is present in the drugs as vardenafil hydrochloride trihydrate, a piperazine derivative and … Vardenafil
Products Mouth sprays are commercially available as drugs, medical devices, and dietary supplements. Listed below are some active ingredients that are administered with an oral spray: Local anesthetics: Lidocaine Disinfectant: chlorhexidine Herbal extracts: chamomile, sage, echinacea. Gel former: celluloses Anti-inflammatory: benzydamine Antibiotics: Tyrothricin Nitrates: isosorbide dinitrate Weaning agents: nicotine Cannabinoids: cannabidiol (CBD), cannabis extract. Mouth … Mouth Sprays
Definition Esters are organic compounds formed by the reaction of an alcohol or phenol and an acid such as a carboxylic acid. The condensation reaction releases a water molecule. The general formula of esters is: esters can also be formed with thiols (thioesters), with other organic acids, and with inorganic acids such as phosphoric acid … Ester
Products Sildenafil is commercially available in the form of film-coated tablets and as a solution for injection (Viagra, Revatio, generics). It has been approved in many countries since 1998. Generics went on sale July 22, 2013, and the patent expired June 21. Pfizer launched auto-generic sildenafil Pfizer, identical to the original, back in May. In … Sildenafil
Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions
