Products Vitamin C is commercially available in the form of tablets, lozenges, effervescent tablets, sustained-release capsules, as a solution for injection, and as a powder, among others. Vitamin C is available as an open product in pharmacies and drugstores. It is also combined fixed with other active ingredients, for example with iron, acetylsalicylic acid, vitamins … Vitamin C
Products Almorexant is not commercially available. Clinical development was discontinued by Actelion and GlaxoSmithKline (GSK) in 2011 due to adverse effects. Structure and properties Almorexant (C29H31F3N2O3, Mr = 512.6 g/mol) is a tetrahydroisoquinoline derivative. It is structurally related to the opioid methopholine. Effects Almorexant has sleep-inducing properties. It is a selective and dual antagonist at … Almorexant
Products Loperamide is commercially available in the form of capsules, film-coated tablets, melting tablets, and as a syrup (Imodium, generic). It has been approved in many countries since 1977. Structure and properties Loperamide (C29H33ClN2O2, Mr = 477.0 g/mol) is a piperidine derivative and has structural similarities to the neuroleptic haloperidol and the peristaltic inhibitor diphenoxylate. … Loperamide: Drug Effects, Side Effects, Dosage and Uses
Definition Active ingredients are the active components of a drug that are responsible for its pharmacological effects. Drugs may contain a single active ingredient, multiple active ingredients, or complex mixtures such as herbal extracts. In addition to the active ingredients, a drug contains various excipients that should be as pharmacologically inert as possible. The percentage … Pharmaceutical Active Ingredient
Products Transdermal fentanyl has been approved in many countries since 1996 (Durogesic, generic). Various strengths are available. The larger the patch, the more fentanyl is released per unit time: 12 µg/h, 25 µg/h, 50 µg/h, 75 µg/h, and 100 µg/h. The opioid is legally classified as a narcotic. Structure and properties Fentanyl (C22H28N2O, Mr = … Fentanyl Patch
Products In many countries, no finished drug products containing levorphanol are on the market. In other countries, products are registered. Structure and properties Levorphanol (C17H23NO, Mr = 257.4 g/mol) is present in the drug as levorphanol tartrate, a white crystalline powder that is soluble in water. It is an opioid and a derivative of morphine. … Levorphanol
Products The fixed combination Targin with the active ingredients oxycodone and naloxone was approved in many countries in 2009. In other countries, the drug is also known as Targinact or Targiniq. In 2016, generic versions were approved in many countries. They went on sale in 2018. Structure and properties Oxycodone (C18H21NO4, Mr = 315.4 g/mol) … Oxycodone, Naloxone
General information Jurnista® is a drug in the analgesic group (analgesics) and is used to treat severe pain. It contains hydromorphone hydrochloride. Contraindications (contraindications) Jurnista® should not be used if any of the following contraindications are met: Absolute contraindication:Jurnista should never be used in infants, children, coma patients, women in labor or during childbirth. Allergy … Jurnista®
Interactions with other drugs If any of the following drugs are taken, the use of Jurnista® should be avoided, as the drugs may influence each other in their effects or increase the risk of side effects occurring MAO inhibitors against depression Morphine-like analgesics (buprenorphine, nalbuphine, pentazocine) Medication for muscle relaxation (e.g. for back pain) Drugs … Interactions with other drugs | Jurnista®
Side effects Particularly frequent side effects when taking Jurnista® are Common side effects are: Unusually strong tiredness, drowsiness, weakness Headache, dizziness Constipation, nausea, vomiting Weight loss, loss of appetite, severe fluid loss, “dehydration Faster heartbeat, lower blood pressure, blushing, high blood pressure Forgetfulness, drowsiness, concentration difficulties Numbness, tingling/ burning skin, muscle trembling/twitching, dullness, changes in … Side effects | Jurnista®
Products Naltrexone is commercially available in the form of film-coated tablets (naltrexin). It has been approved in many countries since 2003. Structure and properties Naltrexone (C20H23NO4, Mr = 341.40 g/mol) is a synthetically produced opioid related to oxymorphone. It is present in drugs as naltrexone hydrochloride, a white, hygroscopic powder that is readily soluble in … Naltrexone
Products Oxymorphone is commercially available in the United States as tablets and sustained-release tablets and has also been administered parenterally and rectally. It is not registered in many countries. Oxymorphone has been approved in the U.S. since 1959 (brand names: Numorphan, Opana, Opana ER, generics). It is a narcotic drug. Due to the potential for … Oxymorphone