peroral

Tenofoviralafenamide

Products Various drugs containing tenofoviralafenamide are on the market worldwide. In many countries, tenofoviralafenamide was first approved in 2016 (United States: 2015). Biktarvy: bictegravir, emtricitabine, and tenofoviralafenamide (HIV). Genvoya: elvitegravir, cobicistat, emtricitabine, and tenofoviralafenamide (HIV). Descovy: emtricitabine and tenofoviralafenamide (HIV). Odefsey: emtricitabine, rilpivirine and tenofoviralafenamide (HIV). Symtuza: darunavir + cobicistat + emtricitabine + tenofoviralafenamide. Vemlidy: … Tenofoviralafenamide

Lactobacilli

Products Lactobacilli are commercially available in the form of capsules, powders, liquids, vaginal tablets and creams, among others. They are pharmaceuticals, dietary supplements, medical devices and cosmetics. Foods such as yogurts and other dairy products also contain lactobacilli. Structure and properties Lactobacilli are Gram-positive, usually rod-shaped, non-spore-forming, and facultatively anaerobic bacteria that belong to the … Lactobacilli

Simeticon

Products Simeticon (simethicone) is commercially available in the form of chewable tablets, as capsules, and as a solution. It has been registered in many countries since 1964. Since the effect is purely physical, medical products are also approved. Structure and properties Simeticone is obtained by incorporating 4 to 7 percent silica into polydimethylsiloxane with a … Simeticon

Naloxone

Products Naloxone is commercially available as a solution for injection (Naloxone OrPha, Naloxone Actavis) and has been approved in many countries since 2004. Information on combination with oxycodone is presented under the article Oxycodone and Naloxone (Targin, Peroral). As a fixed combination with buprenorphine, naloxone is used to treat opioid dependence (Suboxone, sublingual). In 2014, … Naloxone

Naltrexone

Products Naltrexone is commercially available in the form of film-coated tablets (naltrexin). It has been approved in many countries since 2003. Structure and properties Naltrexone (C20H23NO4, Mr = 341.40 g/mol) is a synthetically produced opioid related to oxymorphone. It is present in drugs as naltrexone hydrochloride, a white, hygroscopic powder that is readily soluble in … Naltrexone

Afoxolan

Products Afoxolaner is commercially available in the form of chewable tablets as a veterinary drug for dogs (NexGard). It was approved in many countries in 2015. Structure and properties Afoxolaner (C26H17ClF9N3O3, Mr = 625.9 g/mol) belongs to the isoxazoline group. Effects Afoxolaner (ATCvet QP53BX04) has insecticidal and acaricidal properties. Parasites ingest the active ingredient when … Afoxolan

Delafloxacin

Products Delafloxacin was approved in the United States in 2017, in the EU in 2019, and in many countries in 2020 as a powder for a concentrate for solution for infusion and in tablet form (Quofenix). Structure and properties Delafloxacin (C18H12ClF3N4O4, Mr = 440.8 g/mol) belongs to the group of fluoroquinolones. It is present in … Delafloxacin

Oxymorphone

Products Oxymorphone is commercially available in the United States as tablets and sustained-release tablets and has also been administered parenterally and rectally. It is not registered in many countries. Oxymorphone has been approved in the U.S. since 1959 (brand names: Numorphan, Opana, Opana ER, generics). It is a narcotic drug. Due to the potential for … Oxymorphone