Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses
Products Infliximab is commercially available as a powder for a concentrate for the preparation of an infusion solution (Remicade, biosimilars: Remsima, Inflectra). It has been approved in many countries since 1999. Biosimilars were released in 2015. Structure and properties Infliximab is a chimeric human murine IgG1κ monoclonal antibody with a molecular mass of 149.1 kDa … Infliximab: Drug Effects, Side Effects, Dosage and Uses
Products Valganciclovir is commercially available in the form of film-coated tablets (Valcyte). It has been approved in many countries since 2001. Generic versions were registered in 2014. Structure and properties Valganciclovir (C14H22N6O5, Mr = 354.4 g/mol) is an L-valine ester prodrug of ganciclovir and is present in the drug product as valganciclovir hydrochloride, a white … Valganciclovir
Products Ketazolam is commercially available in capsule form (Solatran). It has been approved in many countries since 1980. Structure and properties Ketazolam (C20H17ClN2O3, Mr = 368.8 g/mol) structurally belongs to the 1,4-benzodiazepines. Effects Ketazolam (ATC N05BA10) has antianxiety, depressant, muscle relaxant, and anticonvulsant properties. The effects are due to binding to GABA-A receptors and enhancement … Ketazolam
Products Nifedipine is commercially available in the form of sustained-release tablets (generics). It was first approved in the mid-1970s. Sales of the original Adalat were discontinued in many countries in 2019. Structure and properties Nifedipine (C17H18N2O6, Mr = 346.3 g/mol) is a dihydropyridine. It exists as a yellow crystalline powder that is practically insoluble in … Nifedipine: Drug Effects, Side Effects, Dosage and Uses
Products (selection) Flawa hemostatic absorbent cotton Dermaplast alginate Stop Hémo nasal tamponade Effects Hemostatic absorbent cotton promotes blood clotting and gels with fluid. Indications Nosebleeds, small superficial bleeding. Substances Most hemostatic absorbent cotton on the market is made of calcium alginate fiber, a plant product derived from algae. Application The required amount is pulled from … Hemostatic Absorbent Cotton
Products Tricyclic antidepressants are commercially available in many countries in the form of dragées, tablets, capsules, and drops. The first representative, imipramine, was developed at Geigy in Basel. Its antidepressant properties were discovered in the 1950s by Roland Kuhn at the psychiatric clinic in Münsterlingen (Thurgau). Imipramine was approved in many countries in 1958. Structure … Tricyclic Antidepressants
Products Insulin detemir is commercially available as an injectable (Levemir). It has been approved in many countries since 2003. Structure and properties Insulin detemir (C267H402O76N64S6, Mr = 5916.9 g/mol) has an identical primary sequence to human insulin except for the removed threonine at position B30 of the B chain and an added molecule of myristic … Insulin Detemir
Products Insulin glargine is commercially available as an injectable (Lantus). It has been approved in many countries since 2002. The biosimilar Abasaglar (LY2963016) was approved in the EU in 2014 and in many countries in 2015. The drugs must be stored between 2 to 8°C in a refrigerator. In 2015, Toujeo was additionally approved in … Insulin Glargine
Products Dactinomycin was commercially available as a lyophilizate (Cosmegen). It was approved in many countries since 1966 and was withdrawn from the market in 2012 on November 30 for commercial reasons. It can be imported from abroad if needed. Structure and properties Dactinomycin (C62H86N12O16, Mr = 1255.4 g/mol) is an actinomycin and phenoxazone derivative formed … Dactinomycin
Products Protamine is commercially available as an injectable. It has been approved in many countries since 1949. Structure and properties Protamine is present in the drug as protamine hydrochloride. It consists of the hydrochlorides of basic peptides with a deep molecular mass and a high arginine content, obtained from sperm or roe of fish (mostly … Protamine
Products Esketamine nasal spray was approved in the US and EU in 2019 and in many countries in 2020 (Spravato). Structure and properties –Ketamine is the pure -enantiomer of ketamine (C13H16ClNO, Mr = 237.7 g/mol). The racemate ketamine is a cyclohexanone derivative derived from phencyclidine (“angel dust”). It is a ketone and an amine and … Esketamine Nasal Spray