Dextromethorphan

Products Dextromethorphan is available in the form of tablets, lozenges, sustained-release capsules, syrup, and drops, among others (in many countries, for example, Bexin, Calmerphan, Calmesin, Pulmofor, combination preparations). The first drugs came on the market in the 1950s. Structure and properties Dextromethorphan (C18H25NO, Mr = 271.4 g/mol) was developed as an analog of codeine and … Dextromethorphan

Ketamine: Drug Effects, Side Effects, Dosage and Uses

Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses

Esketamine Nasal Spray

Products Esketamine nasal spray was approved in the US and EU in 2019 and in many countries in 2020 (Spravato). Structure and properties –Ketamine is the pure -enantiomer of ketamine (C13H16ClNO, Mr = 237.7 g/mol). The racemate ketamine is a cyclohexanone derivative derived from phencyclidine (“angel dust”). It is a ketone and an amine and … Esketamine Nasal Spray

Intoxicant

Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant

Phencyclidine

Products Phencyclidine is not commercially available in many countries. Legally, it is one of the more tightly controlled narcotics and is subject to the relevant legislation. However, it is not a banned substance. Phencyclidine is also illegally manufactured and trafficked. Structure and properties Phencyclidine (C17H25N, Mr = 243.4 g/mol) is a phenylcyclohexylpiperidine. It was originally … Phencyclidine

Rolicyclidine

Products Rolicyclidine is one of the banned narcotics in many countries and is therefore not commercially available. Structure and properties Rolicyclidine (C16H23N, Mr = 229.4 g/mol) is a derivative of phencyclidine (PCP). Instead of a piperidine ring, it contains a pyrrolidine ring. Effects Rolicyclidine has hallucinogenic and depressant properties. Abuse Rolicyclidine can be abused as … Rolicyclidine

Lamotrigine (Lamictal)

Products Lamotrigine is commercially available as tablets and dispersible or chewable tablets (Lamictal, generics). It has been approved in many countries since 1994. Vanillin is typically added to the tablets as a flavoring agent and saccharin as a sweetener. Structure and properties Lamotrigine (C9H7Cl2N5, Mr = 256.1 g/mol) is a chlorinated phenyltriazine derivative that was … Lamotrigine (Lamictal)