Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19
Products Abatacept is commercially available as an injection and infusion preparation (Orencia). It was approved in the United States in 2005 and in the EU and many countries in 2007. Structure and properties Abatacept is a recombinant fusion protein with the following components: Extracellular domain of CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Modified Fc domain of … Abatacept
Products TNF-α inhibitors are commercially available as injectable and infusion preparations. Infliximab (Remicade) was the first agent from this group to be approved in 1998, and in many countries in 1999. Biosimilars of some representatives are now available. Others will follow in the next few years. This article refers to biologics. Small molecules can also … TNF-Α Inhibitors
Symptoms Three different main courses can be distinguished: 1. A mild, local reaction manifests as burning, pain, itching, redness of the skin, and formation of a large wheal. The symptoms improve within 4-6 hours. 2. in a moderately severe course, there is a more severe local reaction, with symptoms such as reddening of the skin … Insect Bites
Effects Carbapenems (ATC J01DH) are bactericidal against aerobic and anaerobic Gram-positive and Gram-negative pathogens. Effects are based on binding to penicillin-binding proteins (PBP) and inhibition of bacterial cell wall synthesis, resulting in bacterial dissolution and death. Imipenem, the first representative of the drug group, is degraded by the renal enzyme dehydropeptidase-I (DHP-I). It is therefore … Carbapeneme
The oral preparatory phase is a part of the swallowing process and brings a bite of food to a state ready for swallowing. This phase is followed by the oral transport phase, during which the swallowing reflex is triggered. Disorders of oral preparation are present, for example, in abnormal saliva production. What is the oral … Oral Preparatory Phase: Function, Tasks, Role & Diseases
Apocrine secretion corresponds to secretion in vesicles. This mode of secretion is relatively rare and occurs primarily in the apical sweat glands. In sweat gland abscess, the affected skin regions are inflamed and trigger fistula formation. What is apocrine secretion? The minor glands of the eyelid follow this mode of secretion, and when inflamed, stye … Apocrine Secretion: Function, Role & Diseases
In apocytosis, the membrane of a glandular cell is sequestered along with the secretion in containers. This is a secretory mode of apocrine glands that is a special form of exocytosis and primarily affects the mammary gland. Disorders of hormonal balance may alter apocytosis behavior. What is apocytosis? It is a secretion mode of apocrine … Apocytosis: Function, Role & Diseases
A dermoid cyst is a cavity lined with epidermal tissue. It is classified as a teratoma. What is a dermoid cyst? A dermoid cyst is a germ cell tumor. Germ cell tumors originate in the germinal tracts. This means that they originate in the ovaries of a woman or the testicles of a man. Germ … Dermoid Cyst: Causes, Symptoms & Treatment
Products Etanercept is commercially available as a solution for injection (Enbrel, biosimilars). It has been approved in many countries since 2000. The biosimilars Benepali and Erlezi were approved in many countries in 2018. Structure and properties Etanercept is a dimeric fusion protein composed of the extracellular ligand-binding domain of TNF receptor-2 and the Fc domain … Etanercept
An ulcer perforation is a tissue breakdown that affects all wall sections of an organ, creating a hole in the organ wall. Ulcers are the cause of this tissue destruction. The stomach or small intestine are most commonly affected by ulcers and, therefore, ulcer perforations. What is an ulcer perforation? An ulcer is an ulcer. … Ulcer Perforation: Causes, Symptoms & Treatment
Megaureter refers to a malformation of the ureter. This causes the ureter to become distended, which can damage the kidneys. What is a megaureter? A megaureter, also known as a megaloureter, is a malformation of the ureter, most of which is already congenital. The malformation is possible on one side or both sides of the … Megaureter: Causes, Symptoms & Treatment
