Saccharomyces Boulardii

Products is commercially available in many countries in the form of capsules and as powder in sachets (Perenterol) and has been approved since 1990. Perenterol travel has been registered and approved for the treatment of traveler’s diarrhea since 2010. In Europe, the fungus has been used as a probiotic since the 1950s. Structure and properties … Saccharomyces Boulardii

Eyebright Eye Drops

Products Eyebright eye drops are available from various suppliers in vials and in the form of single doses. In addition to mono, combination preparations are also commercially available. Ingredients Eye drops contain a dilute or homeopathic preparation of eyebright herb (e.g. , , Scrophulariaceae). Effects Eyebright eye drops are believed to have soothing, moisturizing, anti-inflammatory, … Eyebright Eye Drops

Avanafil

Products Avanafil is commercially available in tablet form (Spedra, some countries: Stendra). It was approved in the US in April 2012, in the EU in 2013, and in many countries in 2016. Structure and properties Avanafil (C23H26ClN7O3, Mr = 483.95 g/mol) is a pyrimidine derivative. It exists as a white crystalline powder that is practically … Avanafil

Avelumab

Products Avelumab was approved in the United States, the EU, and many countries in 2017 as a concentrate for the preparation of an infusion solution (Bavencio). Structure and properties Avelumab is a human IgG1λ monoclonal antibody against programmed cell death ligand 1 (PD-L1) with a molecular weight of 147 kDa. It is produced by biotechnological … Avelumab

Avibactam

Products Avibactam was approved in the United States in 2015, in the EU in 2016, and in many countries in 2019 in fixed combination with the cephalosporin ceftazidime as a powder for a concentrate for solution for infusion (Zavicefta). Structure and properties Avibactam (C7H11N3O6S, Mr = 265.25 g/mol), unlike other beta-lactamase inhibitors, is not itself … Avibactam

Oxytetracycline Eye Ointment

Products No ophthalmic ointments containing oxytetracycline are commercially available in many countries. In Germany, one preparation is available from Jenapharm. Structure and properties Oxytetracycline (C22H24N2O9, Mr = 460.4 g/mol) is present in the ointment as oxytetracycline hydrochloride, a yellow, crystalline, hygroscopic powder that is readily soluble in water. The substance is obtained from certain strains … Oxytetracycline Eye Ointment

Deflazacort

Products Deflazacort is commercially available in tablet form (Calcort). It has been approved in many countries since 1986. Structure and properties Deflazacort (C25H31NO6, Mr = 441.5 g/mol) differs from prednisolone in having an oxazoline ring at C16-C17. Effects Deflazacort (ATC H02AB13) has anti-inflammatory, antiallergic, and immunosuppressive properties. The mineralocorticoid effect of deflazacort is very low. … Deflazacort

Oxytocin Hormone

Products Oxytocin is commercially available as an injectable and nasal spray (syntocinone). It has been approved in many countries since 1956. Generic products are available in many countries. Structure and properties Oxytocin (C43H66N12O12S2, Mr = 1007.2 g/mol) is a cyclic peptide consisting of 9 amino acids (nonapeptide) with a disulfide bridge. The structure of the … Oxytocin Hormone

Degarelix

Products Degarelix is commercially available as a powder and solvent for solution for injection (Firmagon). It was approved in many countries in February 2010. Structure and properties Degarelix is a decapeptide derived from gonadotropin-releasing hormone (GnRH), a hormone of the hypothalamus. It is present in drugs as degarelix acetate and differs from the natural substance … Degarelix

Ozanimod

Products Ozanimod was approved in the United States and many countries in 2020 in hard capsule form (Zeposia). Structure and properties Ozanimod (C23H24N4O3, Mr = 404.5 g/mol) is present in the drug as ozanimod hydrochloride, a white solid that is highly soluble in water. Active metabolites are involved in the effects. Effects Ozanimod (ATC L04AA38) … Ozanimod

Dehydrochloromethyltestosterone

Products In many countries, there are no drugs containing dehydrochlormethyltestosterone on the market. The active ingredient was lanicized in the 1960s and distributed by the state-owned VEB Jenapharm, based in Jena, Thuringia (Oral-Turinabol tablets). Structure and properties Dehydrochloromethyltestosterone (C20H27ClO2, Mr = 334.9 g/mol) is a chlorinated derivative of methyltestosterone. Effects Dehydrochloromethyltestosterone has anabolic and androgenic … Dehydrochloromethyltestosterone

Ozenoxacin

Products Ozenoxacin was approved in the United States in 2017 as a cream (Xepi). Structure and properties Ozenoxacin (C21H21N3O3, Mr = 363.4 g/mol) exists as a white to slightly yellow powder. Unlike most quinolones, it is not fluorinated. Ozenoxacin carries a pyridinyl group at position C-7. Effects Ozenoxacin has bactericidal properties and is effective against … Ozenoxacin