Products Zonisamide is commercially available in the form of capsules (Zonegran). It has been approved in many countries since 2006. Structure and properties Zonisamide (C8H8N2O3S, Mr = 212.2 g/mol) is a benzisoxazole derivative and a sulfonamide. It exists as a white powder that is soluble in water. Effects Zonisamide (ATC N03AX15) has anticonvulsant and antiepileptic … Zonisamide
Products Sulfasalazine is commercially available as tablets and as dragées with an enteric coating (salazopyrin, salazopyrin EN, some countries: azulfidine, azulfidine EN, or RA). It has been approved in many countries since 1950. EN stands for enteric coated and RA for Rheumatoid Arthritis. EN dragées have a coating to prevent irritation and improve gastric tolerance. … Sulfasalazine: Drug Effects, Side Effects, Dosage and Uses
Products Torasemide is commercially available in tablet form (Torem, generic). It has been approved in many countries since 1993. Structure and properties Torasemide (C16H20N4O3S, Mr = 348.4 g/mol) exists as a white powder that is practically insoluble in water. It is a pyridine-sulfonylurea derivative. Torasemide differs structurally from its precursor furosemide (Lasix, generics), a sulfonamide. … Torasemide
Symptoms Toxoplasmosis is usually asymptomatic and unnoticed if the immune status is normal. It may manifest as flu-like symptoms such as muscle and joint pain, sore throat, swollen lymph nodes, headache, fever, and fatigue. The infection leads to immunity. If the immune system is weakened, such as observed in HIV infection and when taking immunosuppressants … Toxoplasmosis Causes and Treatment
Products Trimethoprim and sulfamethoxazole are commercially available in tablet and syrup form (Bactrim, generics). The drug has been approved in many countries since 1969. The Bactrim syrup is no longer available, but a generic is available (Nopil syrup). The fixed combination of the two active ingredients is also called cotrimoxazole. Structure and properties Trimethoprim (C14H18N4O3, … Trimethoprim and Sulfamethoxazole
Products Furosemide is commercially available in the form of tablets, sustained-release capsules, and as a solution for injection (Lasix, generics). It has been approved in many countries since 1964 and is also used in fixed combination with the aldosterone antagonist spironolactone (Lasilactone, generic). Structure and properties Furosemide (C12H11ClN2O5S, Mr = 330.7 g/mol) exists as a … Furosemide: Drug Effects, Side Effects, Dosage and Uses
Products Dorzolamide is commercially available in the form of eye drops (Trusopt). Fixed combinations with timolol (Cosopt) and generics are also available. Dorzolamide has been approved in many countries since 1995. Structure and properties Dorzolamide (C10H16N2O4S3, Mr = 324.4 g/mol) is a sulfonamide. It is present in drugs as dorzolamide hydrochloride, a white crystalline powder … Dorzolamide
Products Piretanide is commercially available in tablet form (Trialix + ramipril). It has been approved in many countries since 1985. In many countries, only the fixed combination with the ACE inhibitor ramipril is currently available. Structure and properties Piretanide (C17H18N2O5S, Mr = 362.40 g/mol) has structural similarities to other loop diuretics and is a sulfonamide. … Piretanide
Products Acetazolamide is commercially available in tablet form and as an injectable (Diamox, Glaupax). It has been approved in many countries since 1955. Structure and properties Acetazolamide (C4H6N4O3S2, Mr = 222.2 g/mol) exists as a white crystalline powder that is very sparingly soluble in water. The sodium salt acetazolamide sodium, which is present in the … Acetazolamide
Products Loop diuretics are commercially available as tablets, sustained-release capsules, and injection and infusion preparations. Torasemide and furosemide are the most commonly used in many countries today. Structure and properties Available loop diuretics are usually sulfonamide or sulfonylurea derivatives. Representatives without a sulfonamide structure also exist, for example, the phenoxyacetic acid derivative etacrynic acid. Effects … Loop Diuretics
Products Pyrimethamine is commercially available in tablet form (Daraprim). The combination Fansidar (+ sulfadoxine) is off the market (malaria). Structure and properties Pyrimethamine (C12H13ClN4, Mr = 248.7 g/mol) is a diaminopyrimidine. It exists as a white crystalline powder or as colorless crystals and is practically insoluble in water. Effects Pyrimethamine (ATC P01BD01) has antiparasitic properties. … Pyrimethamine
