Antifungals

Products Antifungal products are commercially available as creams, ointments, powders, solutions, tablets, capsules, and injectables, among others. Structure and properties The antifungal agents are a structurally heterogeneous class of agents. However, several groups can be identified within the antifungals, such as the azole antifungals and the allylamines (see below). Effects Antifungals have antifungal, fungistatic, or … Antifungals

Administration

Definition and properties The administration or application of a drug refers to its use on the body. The dosage forms (drug forms) used for this purpose consist of the active ingredients and excipients. These include, for example, tablets, capsules, solutions, syrups, injectables, creams, ointments, eye drops, ear drops, and suppositories. Drugs can be liquid, semi-solid, … Administration

EHEC

Symptoms Infection with enterohemorrhagic EHEC manifests as mild, watery to severe, and bloody diarrhea (hemorrhagic colitis). Other possible symptoms include nausea, vomiting, colicky abdominal pain and mild fever. The disease can lead to life-threatening complications, in particular to the hemolytic uremic syndrome HUS. This manifests itself in acute kidney failure, a drop in blood platelets … EHEC

Alkaloids

Products Alkaloids and their derivatives are contained as active ingredients in numerous medicines. They have been used medicinally for thousands of years, such as opium with morphine or coca leaves with cocaine. In 1805, a pure alkaloid was extracted for the first time by the German pharmacist Friedrich Sertürner with morphine. Structure and properties Alkaloids … Alkaloids

Gatifloxacin

Products No drugs containing gatifloxacin are registered in many countries. Eye drops are available in the United States. Tablets and solutions for injection are no longer available because of glucose metabolism disorders (dysglycemia: hypoglycemia, hyperglycemia) that occurred with systemic administration. Gatifloxacin was first approved in 1999. Structure and properties Gatifloxacin (C19H22FN3O4, Mr = 375.4 g/mol) … Gatifloxacin

Ibuprofen Cream

Products Dolocyl cream containing 5% ibuprofen was approved in many countries in 2015 and has been on the market since March 2016. Ibuprofen gels were previously available. Structure and properties Ibuprofen (C13H18O2, Mr = 206.3 g/mol) belongs to the propionic acid derivative group and is a racemate. It exists as a white crystalline powder or … Ibuprofen Cream

Lozenges

Products There are many lozenges available in the market. They are medicines, medical devices or dietary supplements. Structure and properties Lozenges are solid and single-dose preparations intended for sucking. They contain one or more active ingredients, usually in a flavored or sweetened base, and they are intended to dissolve or or disintegrate slowly in the … Lozenges

Dehydroepiandrosterone (DHEA)

Products Vaginal suppositories containing dehydroepiandrosterone were registered in many countries in 2020 (Intrarosa). The active ingredient is referred to as prasterone in medications. Furthermore, an intramuscular injection solution containing the prodrug prasterone antate has been registered in many countries (Gynodian Depot). In the United States, dietary supplements (“dietary supplements”) containing dehydroepiandrosterone (DHEA) have been allowed … Dehydroepiandrosterone (DHEA)