Products Dihydrotachysterol is commercially available as an oily solution (A.T. 10). It has been approved in many countries since 1952. Structure and properties Dihydrotachysterol (C28H46O, Mr = 398.7 g/mol) is a lipophilic analog of vitamin D. Effects Dihydrotachysterol (ATC A11CC02) has multiple properties in calcium metabolism. The compound is already active and does not need … Dihydrotachysterol
Products Thiazide diuretics are commercially available in tablet form. Chlorothiazide (Diuril) and the closely related and more potent hydrochlorothiazide were the first of this group to enter the market in the 1950s (Switzerland: Esidrex, 1958). However, other related thiazide-like diuretics are available (see below). In English, we speak of (thiazide diuretics) and (thiazide-like diuretics). Numerous … Thiazide Diuretics
Products Tacalcitol is commercially available as an ointment and lotion (Curatoderm). It has been approved in many countries since 1995. Structure and properties Tacalcitol (C27H44O3, Mr = 416.6 g/mol) is a derivative of vitamin D3. It is lipophilic and is present in drugs as tacalcitol monohydrate. Effects Tacalcitol (ATC D05AX04) inhibits the proliferation of keratinocytes … Tacalcitol
Products Calcifediol was approved in the United States in 2016 and in many countries in 2020 in extended-release capsule form (Rayaldee). Structure and properties Calcifediol (C27H44O2, Mr = 400.6 g/mol) is a hydroxylated derivative of vitamin D3 (cholecalciferol). It is 25-hydroxycholecalciferol or 25-hydroxyvitamin D3. Calcifediol is present in the drug as calcifediol monohydrate, a white … Calcifediol
Products Clopamide was commercially available in tablet form and exclusively in combination with other agents (Brinerdin, Viskaldix, off label). Structure and properties Clopamide (C14H20ClN3O3S, Mr = 345.8 g/mol) is a sulfonamide derivative. Effects Clopamide (ATC C03BA03) has diuretic and antihypertensive properties. It promotes excretion of water and sodium by inhibiting reabsorption. Indications In combination preparations: … Clopamide
Products Calcium is commercially available in numerous drug products as a monopreparation, a fixed combination with vitamin D (usually cholecalciferol), and other vitamins and minerals. The most commonly used dosage forms include chewable, lozenge, meltable and effervescent tablets. Film-coated tablets that can be swallowed whole have also been available for some time. Structure and properties … Calcium Health Effects
Products Calcium carbonate is commercially available as a drug in the form of tablets, capsules, effervescent tablets, chewable tablets, lozenges, and oral suspension, among others. Some products are combination preparations, for example with vitamin D3 or other antacids. Structure and properties Calcium carbonate (CaCO 3 , M r = 100.1 g/mol) exists in pharmacopoeia quality … Calcium Carbonate
Products Hydrochlorothiazide is commercially available in numerous antihypertensive agents in combination with ACE inhibitors, sartans, renin inhibitors, potassium-sparing diuretics, calcium channel blockers, and beta blockers. Use as a monopreparation (Esidrex) is less common. Hydrochlorothiazide has been approved in many countries since 1958. Structure and properties Hydrochlorothiazide (C7H8ClN3O4S2, Mr = 297.7 g/mol) is a white crystalline … Hydrochlorothiazide
Products Xipamide is not currently registered or commercially available in many countries. In Germany and Austria, it is available in tablet form (Aquaphor, Aquaphoril, generics). Structure and properties Xipamide (C15H15ClN2O4S, Mr = 354.8 g/mol) has a sulfonamide structure and is structurally related to the thiazides, but acts from the blood side. It exists as a … Xipamide
Symptoms Photosensitivity often manifests like sunburn in extensive skin redness, pain, a burning sensation, blistering, and hyperpigmentation after healing. Other possible skin reactions include eczema, itching, urticaria, telangiectasia, tingling, and edema. The nails may also be affected less frequently and may peel off in front (photoonycholysis). The symptoms are limited to the areas of the … Photosensitivity
Products Diuretics are mainly administered in the form of tablets. In addition, injectables are also commercially available. Among the most commonly prescribed diuretics are loop diuretics (torasemide). Effects Diuretics (ATC C03) have diuretic and antihypertensive properties. Through various mechanisms, they cause increased excretion of water and electrolytes in the urine. They are active at the … Diuretics (Water Pills): Effects, Side Effects, Dosage and Uses
Products Trichloromethiazide is marketed as granules in combination with dexamethasone. It has been approved in many countries since 2008. Structure and properties Trichloromethiazide (C8H8Cl3N3O4S2, Mr = 380.7 g/mol) has a sulfonamide structure. Effects Trichloromethiazide (ATC QC03AA56) has diuretic properties. Indications Peripartum udder edema in cattle.
