Products Cladribine was approved for the treatment of multiple sclerosis in the EU in 2017 and in the United States and many countries in 2019 in tablet form (Mavenclad). Cladribine has also been commercially available as an infusion and injection solution in many countries since 1998 (Litak). This article relates to MS therapy. Structure and … Cladribine
Products Bumetanide was commercially available in tablet form (Burinex, off label). It was approved in many countries in 1974. Structure and properties Bumetanide (C17H20N2O5S, Mr = 364.4 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Bumetanide (ATC C03CA02) is diuretic with rapid onset and short duration of action. Indications Oedema … Bumetanide
Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin
Products Bunazosin is commercially available in the form of sustained-release tablets (Andante). The drug is not registered in many countries. Structure and properties Bunazosin (C19H27N5O3, Mr = 373.4 g/mol) is present in drugs as bunazosin hydrochloride. It is a quinazoline derivative. Effects Bunazosin (ATC C02CA) is antihypertensive. Its effects are due to selective and competitive … Bunazosin
Products Clascoterone was approved as a cream in the United States in 2020 (Winlevi). Structure and properties Clascoterone (C24H34O5, Mr = 402.5 g/mol) corresponds to the steroid cortexolone-17α-propionate. It exists as a white powder that is practically insoluble in water. Effects Clascoterone has antiandrogenic properties. The effects are due to antagonism at androgen receptors. Androgens … Clascoteron
