Purine is an organic compound and a heteroaromatic with four nitrogen atoms, becomes the finished purine nucleus by five additional carbon atoms and forms the basic body of the entire substance group of purines. The latter are important building blocks of nucleic acids and at the same time the stores of hereditary information. Purines are … Purine: Function & Diseases
Gout, one of today’s common diseases, is associated with an unbalanced diet rich in meat and alcohol consumption. Along with other diseases, gout is one of the manifestations of rheumatism. A targeted healthy diet can positively influence the course of gout and even reduce symptoms of this rheumatic disease. But what to eat for gout … Gout Diet Guideline
Products Lesinurad was approved in the US in 2015, in the EU in 2016, and in many countries in 2017 in film-coated tablet form (Zurampic). A fixed-dose combination with allopurinol was released in the US in 2017 (Duzallo), in the EU in 2018, and in many countries in 2019. Structure and properties Lesinurad (C17H14BrN3O2S, Mr … Lesinurad
Gout is a disease caused by a disturbance in the metabolism of uric acid. It leads to an increased attack of uric acid, which can no longer be excreted sufficiently via the kidneys. This leads to the formation of so-called urate crystals, which settle on various joints of the body and cause pain. The classic … Home remedy against gout
Gout in the foot A frequent manifestation site, i.e. a place where the symptoms of gout occur, is the foot. The metatarsophalangeal joint of the big toe is particularly affected. Especially in acute attacks of gout, strong pain can occur, which can severely limit the affected person. The pain occurs more frequently at night, but … Gout in the foot | Home remedy against gout
Treatment of the disease only with home remedies or only as supportive therapy? Whether or not treatment of gout is only possible with home remedies depends on the nature of the symptoms. In principle, the pain of an acute attack of gout can be alleviated with home remedies, but often an additional intake of painkillers … Treatment of the disease only with home remedies or only as supportive therapy? | Home remedy against gout
Which homeopathics can help me? Various homeopathic drugs can be used in the case of gout disease. These include Adlumia, which can also be used for liver and kidney diseases. It promotes the transport and elimination of toxic substances from the body and is recommended with potencies D4 to D12. Calcium fluoratum is a homeopathic … Which homeopathics can help me? | Home remedy against gout
Probenecid is a second-line drug for hyperuricemia and gout. It inhibits the URAT1 exchanger in the kidney, increasing the release of urea into the urine while decreasing the excretion of organic anions. Probenecid interacts with numerous other drugs. What is probenecid? Because the drug stimulates the body to excrete uric acid, probenecid belongs to the … Probenecid: Effects, Uses & Risks
Hypoxanthine, along with xanthine, is a breakdown product from purine metabolism. It is further degraded into uric acid. Diseases can occur both when its degradation to uric acid is inhibited and when its recycling via the salvage pathway is impaired. What is hypoxanthine? Hypoxanthine is a purine derivative and is formed during the degradation of … Hypoxanthine: Function & Diseases
Products Rasburicase is commercially available as an injectable (Fasturtec). It has been approved in many countries since 2002. Structure and properties Rasburicase is a recombinant urate oxidase enzyme produced by a genetically modified strain of yeast. Effects The enzyme rasburicase (ATC V03AF07) catalyzes the enzymatic oxidation of uric acid into allantoin, a water-soluble substance that, … Rasburicase
Products Enzymes are commercially available as drugs in the form of tablets, lozenges, capsules, as well as injection and infusion preparations, among others. Many products are subject to prescription, but there are also some agents which are released for the OTC market. Structure and properties Therapeutic enzymes are usually proteins, i.e. polymers of amino acids, … Therapeutic Enzymes
Products Allantoin is found in creams and ointments for external use and in numerous cosmetics and personal care products. Structure and properties Allantoin (C4H6N4O3, Mr = 158.12 g/mol) is a racemate and belongs to the group of imidazolidines. It is present white, crystalline powder and is odorless and tasteless. It is sparingly soluble in water. … Allantoin
