Hepatitis A Vaccine

Products Hepatitis A vaccine is commercially available as an injection suspension (Havrix). It has been licensed in many countries since 1993. A fixed combination with hepatitis B vaccine is also available (Twinrix). Structure and properties Hepatitis A vaccine is either hepatitis A virus inactivated with formaldehyde or a liposomal preparation of hepatitis A virus antigen. … Hepatitis A Vaccine

Hepatitis b Vaccine

Products Hepatitis B vaccine is licensed as an injectable in many countries (e.g., Engerix-B, combination products). Structure and properties The vaccine contains a the highly purified surface antigen HBsAg of hepatitis B virus. HBsAg is produced by biotechnological methods. It is a membrane protein localized on the viral envelope of hepatitis B virus. Effects Hepatitis … Hepatitis b Vaccine

Shake Before Use

Background Numerous drugs exist that must be shaken well immediately before administration. These include, for example, certain eye drops, nasal sprays, injectables, and antibiotic suspensions for children (see below). The reason is usually that the active ingredient in the drug is in suspension. Suspensions are heterogeneous mixtures of substances consisting of a liquid in which … Shake Before Use

Anthrax Symptoms, Causes and Treatment

Symptoms Depending on the organs affected, the following clinical pictures are distinguished: Cutaneous anthrax Pulmonary anthrax Gastrointestinal anthrax Injection anthrax is observed when contaminated illicit heroin is injected intravenously. Typical symptoms of anthrax include fever, aching limbs, headache, sweating, chills and edema. Anthrax can lead to blood poisoning, meningitis, and organ failure, among other symptoms, … Anthrax Symptoms, Causes and Treatment

BNT162b2 (Tozinameran)

Products BNT162b2 from German biotechnology company BioNTech and Pfizer was approved in many countries on December 19, 2020, as the first representative of mRNA vaccines and Covid-19 vaccines (Comirnaty, frozen suspension). The vaccine was studied in 2020 in a large Phase III trial with more than 44,000 participants. Switzerland was the first country in which … BNT162b2 (Tozinameran)

Interferon Gamma-1B

Products Interferon gamma is commercially available as a solution for injection (Imukin). It has been approved in many countries since 1997. Structure and properties Interferon gamma-1b is a protein consisting of 140 amino acids. It is obtained from a -strain by biotechnological methods. Effects Interferon gamma (ATC L03AB03) has antiviral, antiproliferative, antitumor, and immunostimulatory properties. … Interferon Gamma-1B

Intramuscular Injection

Definition In an intramuscular injection, a drug is administered into a skeletal muscle using a syringe and cannula. From the muscle, it enters the bloodstream through the vessels and is distributed throughout the body. Application sites A common site of application for small volumes of up to 2 ml is the deltoid muscle of the … Intramuscular Injection

Bacterial Meningitis

Symptoms Typical symptoms of bacterial meningitis include high fever, severe headache, and neck stiffness. However, these symptoms do not necessarily all have to be present. The disease may be accompanied by nausea, vomiting, skin rash, petechiae, sensitivity to light, and clouding of consciousness, among other symptoms. The infection can lead to blood poisoning and other … Bacterial Meningitis

Therapeutic Proteins

Products Therapeutic proteins are usually administered in the form of injection and infusion preparations and must be stored in a refrigerator. The first recombinant protein to be approved was human insulin in 1982. Some proteins, for example, are also available in tablet, capsule, and powder form and can be stored at room temperature, such as … Therapeutic Proteins

Administration

Definition and properties The administration or application of a drug refers to its use on the body. The dosage forms (drug forms) used for this purpose consist of the active ingredients and excipients. These include, for example, tablets, capsules, solutions, syrups, injectables, creams, ointments, eye drops, ear drops, and suppositories. Drugs can be liquid, semi-solid, … Administration