Quinolone

Products The first active ingredient in the quinolone group to be introduced was nalidixic acid in 1967 (NegGram). It is no longer commercially available in many countries. Other drugs are available today (see below). Various dosage forms are available, for example, film-coated tablets, oral suspensions, eye drops, ear drops, and infusion solutions. Due to adverse … Quinolone

Acute Sinusitis

Anatomical background Humans have 4 sinuses, the maxillary sinuses, the frontal sinuses, the ethmoid sinuses, and the sphenoid sinuses. They are connected to the nasal cavity by 1-3 mm narrow bony openings called ostia and are lined with a thin respiratory epithelium with goblet cells and seromucous glands. The ciliated hairs provide clearance of mucus … Acute Sinusitis

Azole Antifungals

Products Azole antifungals are approved in many countries for both topical and systemic treatment. They are available in numerous dosage forms-including creams, an oral gel, powders, sprays, tablets, capsules, injectables, vaginal creams, and vaginal tablets. The first azole antifungal came on the market in the 1950s. Structure and properties The name azole refers to heterocycles … Azole Antifungals

Trichomoniasis

Symptoms In women, trichomoniasis manifests as inflammation of the vaginal mucosa with redness, swelling, and a frothy, thin, yellowish-green, foul-smelling discharge. The urethra and cervix may also be infected. The type of discharge varies. In addition, there may be itching, small skin bleeding, and pain during sexual intercourse and urination. In men, the disease is … Trichomoniasis

Tea Tree Oil: Medicinal Uses

Products The pure tea tree oil is available in pharmacies and drugstores. There are numerous products with the essential oil on the market, for example, body care products, lip balms, mouthwashes and toothpastes. These are usually not registered medicines. Structure and properties Tea tree oil is the essential oil obtained by steam distillation from the … Tea Tree Oil: Medicinal Uses

Econazole

Products Econazole is commercially available as a cream, powder, pump spray, vaginal cream, and vaginal suppository (Pevaryl, Gyno-Pevaryl, Pevisone + triamcinolone acetonide). The active ingredient has been approved in many countries since 1974. Structure and properties The imidazole derivative econazole (C18H15Cl3N2O, Mr = 381.7 g/mol) is a white powder that is practically insoluble in water. … Econazole

Miconazole

Products Miconazole is available as a cream, miconazole mouth gel and shampoo, and commercially (e.g., Daktarin). It has been approved in many countries since 1972. This article refers to external therapy. See also under miconazole mouth gel and miconazole for nail fungus. The nail tincture for nail fungus treatment is no longer marketed in many … Miconazole

Contraceptive Ring

Products The progestin etonogestrel and the estrogen ethinylestradiol are commercially available in the form of a vaginal contraceptive ring (NuvaRing). The drug has been approved in many countries since 2003. Generics have also been registered since 2017. Whether the contraceptive ring needs to be stored in the refrigerator depends on the product. Meanwhile, medicines are … Contraceptive Ring

Fluconazole

Products Fluconazole is commercially available in capsule form, as a powder for suspension, and as an infusion solution (Diflucan, generic). It has been approved in many countries since 1989. Structure and properties Fluconazole (C13H12F2N6O, Mr = 306.3 g/mol) is a fluorinated triazole derivative. It exists as a white, crystalline and hygroscopic powder that is sparingly … Fluconazole

Clindamycin Vaginal Cream

Products Clindamycin vaginal cream has been approved in many countries since 1995 (Dalacin V). Structure and properties Clindamycin (C18H33ClN2O5S, Mr = 425.0 g/mol) is a derivative of lincomycin (7-chloro-7-deoxy-lincomycin) obtained from. It is present in vaginal cream as clindamycin phosphate, a white, slightly hygroscopic powder that is readily soluble in water. Effects Clindamycin (ATC G01AA10) … Clindamycin Vaginal Cream

Norfloxacin

Products Norfloxacin is commercially available in the form of film-coated tablets. It was approved in many countries in 1983. The original product, Noroxin, is no longer available, but generics are available. Structure and properties Norfloxacin (C16H18FN3O3, 319.33 g/mol) is a fluoroquinolone. It exists as a white to pale yellow, hygroscopic, photosensitive crystalline powder that is … Norfloxacin

Yeast infection

What is a yeast infection? An infection with a yeast fungus is a clinical picture which is caused by yeasts. The shoot fungi can generally be assigned to the fungi. The fungi, in turn, form a parent group of microbiology alongside bacteria, viruses, protozoa and algae. To the yeast fungi (shoot fungi) belong, as the … Yeast infection