Coxsackie

Coxsackie A/B: Diagnostic Tests

Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics, and obligatory medical device diagnostics – for differential diagnostic clarification. Computed tomography (CT; sectional imaging procedure (X-ray images taken from different directions with computer-based evaluation)) – for suspected CNS involvement such as meningitis (meningitis). Electrocardiogram (ECG; recording of the … Coxsackie A/B: Diagnostic Tests

Coxsackie A/B: Causes

Pathogenesis (disease development) Coxsackie virus infections (virus family: Picorna virus) are transmitted primarily fecal-orally, but also via infected food. Aerogenic – via the air – and placental – via the placenta (placenta) – transmission also play a role. Etiology (causes) Biographic causes Socioeconomic factors – low socioeconomic status. Low standard of hygiene Behavioral causes Compliance … Coxsackie A/B: Causes

Coxsackie A/B: Therapy

General measures Observance of the general hygiene measures! In the occurrence of fever: Bed rest and physical rest (even if fever is only mild; if limb pain and lassitude occur without fever, bed rest and physical rest is also required, because myocarditis/heart muscle inflammation could occur as a result of the infection). Fever below 38.5 … Coxsackie A/B: Therapy

Coxsackie A/B: Symptoms, Complaints, Signs

For the most part, the infection is asymptomatic (60%), meaning that it causes no symptoms at all. When symptoms do occur, they are usually very nonspecific. The following symptoms and complaints may indicate Coxsackie A infection: Bronchitis Cephalgia (headache) Diabetes mellitus type 1 Exanthem (rash) – patchy rash associated with papule (vesicle) formation. Fever Hand-foot-mouth … Coxsackie A/B: Symptoms, Complaints, Signs

Coxsackie A/B: Medical History

Medical history (history of illness) represents an important component in the diagnosis of Coxsackie virus infection. Family history What is the general health status of your relatives? Social history Have you been abroad recently? What were the local hygienic conditions like? Current medical history/systemic history (somatic and psychological complaints). Have you noticed any flu-like symptoms … Coxsackie A/B: Medical History

Coxsackie A/B: Or something else? Differential Diagnosis

Diseases to consider for differential diagnosis of coxsackie A virus infection:Infectious and parasitic diseases (A00-B99). Infectious diseases of other genesis Diseases to be considered for differential diagnosis of Coxsackie B virus infection: Respiratory system (J00-J99) Mediastinitis – inflammation of the mediastinum (middle pleural space). Pleurisy (inflammation of the pleura) Pneumothorax – collapse of the lungs … Coxsackie A/B: Or something else? Differential Diagnosis

Coxsackie A/B: Complications

The following are the most important diseases or complications that may be contributed to by Coxsackie virus infections: Endocrine, nutritional, and metabolic diseases (E00-E90). Diabetes mellitus type 1 Thyroiditis (inflammation of the thyroid gland) Skin and subcutaneous (L00-L99) Acquired onychodystrophy (pathologic nail growth) of both great toenails with onychomadesis (proximal detachment of the nail plate … Coxsackie A/B: Complications

Coxsackie A/B: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further: Inspection (viewing). Skin, mucous membranes, oral cavity, and sclera (white part of the eye) [maculopapular exanthema (rash) – patchy rash accompanied by papule (vesicle) formation; herpangina (vesicle on … Coxsackie A/B: Examination

Coxsackie A/B: Test and Diagnosis

1st order laboratory parameters Coxsackie virus A2 antibody; coxsackie virus B1-B6 antibody (CSF/serum). Coxsackie virus antibody (IgA) – positive IgA detection indicates active infection. Coxsackie virus antibody (IgG) – seroconversion with IgG detection or a significant IgG titer increase during the course indicate active infection. Coxsackie virus antibody (IgM) – positive IgM detection indicates active … Coxsackie A/B: Test and Diagnosis

Coxsackie A/B: Drug Therapy

Therapeutic targets Improvement of the symptomatology Avoidance of complications Therapy recommendations Symptomatic therapy (analgesics/pain relievers or anti-inflammatories/anti-inflammatory drugs (non-steroidal anti-inflammatory drugs (NSAIDs), anti-emetics/anti-nausea and anti-nausea drugs), as appropriate). Antivirals (are currently being tested). Gamma globulin preparations (preferably from convalescent sera/blood serum used for passive immunization and derived from people who have just survived a specific … Coxsackie A/B: Drug Therapy