Products Piperacillin is commercially available as an injectable (tazobac + tazobactam, generics). It has been approved in many countries since 1992. Structure and properties Piperacillin (C23H27N5O7S, Mr = 517.6 g/mol) is present in drugs as piperacillin sodium, a white crystalline powder that is readily soluble in water. Tazobactam (C10H12N4O5S, Mr = 300.3 g/mol) also exists … Piperacillin
Products Benzylpenicillin (penicillin G) is commercially available as an injectable (Penicillin Grünenthal). Structure and properties Benzylpenicillin (C16H18N2O4S, Mr = 334.4 g/mol) is present in the drug as benzylpenicillin sodium, a white crystalline powder that is very soluble in water. Other salts are also available. Benzylpenicillin is not acid stable, has low absorption, and therefore can … Benzylpenicillin
Products Phenoxymethylpenicillin is commercially available in the form of film-coated tablets and as a syrup. It has been approved in many countries since 1961 (Ospen). Structure and properties Phenoxymethylpenicillin or pencillin V (C16H18N2O5S, Mr = 350.4 g/mol) is present in the tablets as phenoxymethylpenicillin potassium, a white crystalline powder that is readily soluble in water. … Phenoxymethylpenicillin
Products Imipenem is commercially available as an infusion preparation and fixed combination with cilastatin (Tienam, generics). Imipenem was approved in many countries in 1985 as the first member of the carbapenems. Structure and properties Imipenem (C12H17N3O4S, Mr = 299.3 g/mol) is present in drugs as imipenem monohydrate, a white or pale yellow powder that is … Imipenem
Products Flucloxacillin is commercially available in capsule form and as an injectable (floxapen, generic). It has been approved in many countries since 1972. Structure and properties Flucloxacillin (C19H17ClFN3O5S, Mr = 453.9 g/mol) is present in drugs as the sodium salt flucloxacillin sodium, a white, crystalline, and hygroscopic powder that is readily soluble in water. Flucloxacillin … Flucloxacillin
Side effect The side effects of betalactamase inhibitors are due to their antibacterial effect. Therefore, betalactamase inhibitors cause the same side effects as the antibiotics with which they are co-administered. During therapy with antibiotics and betalactam inhibitors, the bacteria that cause an infection are fought by the active ingredients. This is the desired effect. However, … Side effect | Betalactamase inhibitors
Price The price of betalactamase inhibitors is difficult to determine. Betalactamase inhibitors are usually offered in combination with antibiotics. The price of the combination depends on the dosage and the amount of tablets contained in a package. Liquid solutions of the combination of active substances, for example for intravenous therapy (therapy with the antibiotic and … Price | Betalactamase inhibitors
Effectiveness of the pill when taking beta-lactam inhibitors The effectiveness of the pill may be limited when treated with beta-lactamase inhibitors. This is due to the fact that the active ingredients sometimes undergo similar metabolic processes in the body and thus influence each other when they are present in the body at the same time. … Effectiveness of the pill when taking beta-lactam inhibitors | Betalactamase inhibitors
What are betalactamase inhibitors? Betalactamase inhibitors are active ingredients used in combination with antibiotics to treat certain types of bacteria. Betalactamase inhibitors are drugs that are directed against a defence mechanism of bacteria against the traditional antibiotics such as penicillins and cephalosporins. Thus, antibiotic therapy can also be used to treat bacterial species that defend … Betalactamase inhibitors
