Sleeping Sickness (African Trypanosomiasis): Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps:

  • General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further:
    • Inspection (viewing).
      • Skin, mucous membranes and sclerae (white part of the eye) [primary lesion (trypanosome chancre) at the site of pathogen invasion (sting, wound, etc.) – heals spontaneously after a few weeks; exanthema (rash): truncal, itchy, annular (ring-shaped); lymphadenopathy (lymph node enlargement), especially of the nuchal lymph nodes; anemia (anemia)]
      • Abdomen (abdomen)
        • Shape of the abdomen?
        • Skin color? Skin texture?
        • Efflorescences (skin changes)?
        • Pulsations? Bowel movements?
        • Visible vessels?
        • Scars? Hernias (fractures)?
    • Auscultation (listening) of the heart.
    • Auscultation of the lungs
    • Abdominal (stomach) examination [hepatosplenomegaly (liver and spleen enlargement)?]
      • Percussion (tapping) of the abdomen.
        • Meteorism (flatulence): hypersonoric tapping sound.
        • Attenuation of tapping sound due to enlarged liver or spleen, tumor, urinary retention?
        • Hepatomegaly (liver enlargement) and/or splenomegaly (spleen enlargement): estimate liver and spleen size.
      • Palpation (palpation) of the abdomen (tenderness?, knocking pain?, coughing pain?, defensive tension?, hernial orifices?, renal bearing knocking pain?).
  • Neurological examination – checking reflexes, strength, orientation, etc. [Meningoencephalitic stage (after months/years in the West African form; much faster in the East African form)]