The following are the most important diseases or complications that may be contributed to by brucellosis: Respiratory system (J00-J99) Pneumonia (pneumonia) Eyes and eye appendages (H00-H59). Uveitis – inflammation of the middle eye skin. Blood, blood-forming organs – immune system (D50-D90). Anemia (anemia) Leukocytopenia – decrease in white blood cells (leukocytes). Thrombocytopenia – decrease in … Brucellosis: Consequential Diseases
Pathogenesis (development of disease) The virus replicates (multiplies) locally in mucosal cells. It then invades the nerve cell processes and from there into the corresponding ganglion (cluster of nerve cell bodies in the peripheral nervous system), where they remain dormant until reactivated by various stressors. Etiology (causes) Behavioral causes Diet Micronutrient deficiency (vital substances) – … Herpes Simplex Virus: Causes
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye) [primary lesion (trypanosome chancre) at the site of pathogen invasion (sting, wound, etc.) – heals spontaneously … Sleeping Sickness (African Trypanosomiasis): Examination
Blood, blood-forming organs-immune system (D50-D90). Sarcoidosis – inflammatory systemic disease affecting primarily the skin, lungs, and lymph nodes. Endocrine, nutritional and metabolic diseases (E00-E90). Amyloidosis – extracellular (“outside the cell”) deposits of amyloids (degradation-resistant proteins) that can lead to cardiomyopathy (heart muscle disease), neuropathy (peripheral nervous system disease), and hepatomegaly (liver enlargement), among other conditions. … Pericarditis: Or something else? Differential Diagnosis
To prevent reaction to insect venoms, attention must be paid to reducing individual risk factors. Disease-related risk factors. Injuries, poisonings, and other consequences of external causes (S00-T98). Insect bite Risk factors of frequent bee/wasp sting exposure Biographic risk factors Occupations Beekeeper Bakery salesman Construction worker Firefighter Gardener Farmers Truck drivers Fruit seller Forestry worker Family … Insect Bites: Prevention
Infectious and parasitic diseases (A00-B99). Infectious mononucleosis (Pfeiffeŕsches glandular fever; EBV infection; Epstein-Barr virus infection). Neoplasms – tumor diseases (C00-D48). Other forms of leukemia
1st order laboratory parameters – obligatory laboratory tests. Biopsy (tissue sample) – characteristic of malignant fibrous histiocytoma is pleomorphy (nuclei of similar cells take on a different appearance): the cells resemble a fibroblast (connective tissue cell) on the one hand and a histiocyte (resident phagocyte) on the other. Caveat: Because other sarcomas also contain pleomorphic … Malignant Fibrous Histiocytoma: Test and Diagnosis
Therapeutic Targets Avoidance of complications and sequelae such as esophageal variceal or fundus variceal hemorrhage. In variceal bleeding: hemostasis. Avoidance of sepsis (blood poisoning). Avoidance of recurrent bleeding (bleeding again). Therapy recommendations Reduction of portal pressure via reduction of portal-venous inflow → improved prognosis: fewer complications of portal hypertension and consequently reduced mortality (morbidity). Suitable … Portal Hypertension: Drug Therapy
2nd order laboratory parameters – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification. Small blood count Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate). Urine status (rapid test for: pH, leukocytes, nitrite, protein, blood), sediment, if necessary urine culture (pathogen detection and … Anal Discomfort (Anorectal Pain): Test and Diagnosis
To prevent herpes simplex infection, attention must be paid to reducing risk factors. Behavioral risk factors Diet Micronutrient deficiency (vital substances) – see Prevention with micronutrients. Close physical contact Sexual contact The following factors may promote reactivation: Biographical risk factors Hormonal changes such as menstruation (period). Behavioral risk factors Psycho-social situation Stress UV radiation Disease-related … Herpes Simplex Virus: Prevention
Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). Abetalipoproteinemia (synonym: homozygous familial hypobetalipoproteinemia, ABL/HoFHBL) – genetic disorder with autosomal recessive inheritance; severe form of familial hypobetalipoproteinemia characterized by deficiency of apolipoprotein B48 and B100; defect in the formation of chylomicrons leading to fat digestion disorders in children, resulting in malabsorption (disorder of food absorption). Endocrine, nutritional … Fatty Stools (Steatorrhea): Or something else? Differential Diagnosis
Obligatory medical device diagnostics. Abdominal sonography (ultrasound examination of abdominal organs) – for basic diagnostics. Computed tomography (CT) of the abdomen (abdominal CT). Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics and obligatory medical device diagnostics – for differential diagnostic clarification. Endoscopic retrograde cholangiopancreaticography (ERCP; diagnostic method … Fatty Stools (Steatorrhea): Diagnostic Tests
