The following are the most important diseases or complications that may be contributed to by stress:
Blood, blood-forming organs – Immune system (D50-D90).
- Immunodeficiency (including susceptibility to infection).
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Andropause (male menopause)
- Hypercholesterolemia – lipid metabolism disorder (fat metabolism disorder) characterized by elevated levels of cholesterol in the blood.
- Hyperhomocysteinemia (increased homocysteine levels in the blood).
- Hyperprolactinemia (increased prolactin level in the blood).
- Hypertriglyceridemia (increased triglyceride levels in the blood.
- Metabolic syndrome – clinical name for the symptom combination of obesity (overweight), hypertension (high blood pressure), elevated fasting glucose (fasting blood sugar) and fasting insulin serum levels (insulin resistance) and dyslipidemia (elevated VLDL triglycerides, lowered HDL cholesterol). Furthermore, a coagulation disorder (increased tendency to clotting), with an increased risk of thromboembolism is also often detectable
- Somatopause (growth hormone deficiency).
- Overweight (obesity)
Skin and subcutaneous (L00-L99)
- Alopecia (here: diffuse hair loss).
- Atopic eczema (neurodermatitis)
- Seborrheic eczema (seborrheic dermatitis)
Cardiovascular system (I00-I99)
- Arterial hypertension (high blood pressure).
- Apoplexy/stroke (large vessel disease; small vessel disease; crytogenic stroke).
- Atherosclerosis (arteriosclerosis, hardening of the arteries).
- Coronary heart disease (CHD) – disease in which there is a lack of oxygen supply to the heart muscle due to a narrowing of the coronary arteries (arteries that surround the heart in a wreath shape and supply the heart muscle with blood).
- Myocardial infarction (heart attack).
- Atrial fibrillation (VHF)
Infectious and parasitic diseases (A00-B99).
- Infectious diseases, unspecified
Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).
- Dysbiosis (imbalance of intestinal flora).
- Functional dyspepsia (irritable stomach)
- Gastritis (inflammation of the gastric mucosa)
- Gastroesophageal reflux disease (synonyms: GERD, gastroesophageal reflux disease; gastroesophageal reflux disease (GERD); gastroesophageal reflux disease (reflux disease); gastroesophageal reflux; reflux esophagitis; reflux disease; Reflux esophagitis; peptic esophagitis) – inflammatory disease of the esophagus (esophagitis) caused by the pathological reflux (reflux) of acid gastric juice and other gastric contents.
- Gingivitis (inflammation of the gums)
- Gastrointestinal disorders, unspecified
- Periodontitis – disease of the periodontium.
- Pulpitis (inflammation of the dental nerve)
- Irritable bowel syndrome (synonyms: irritable colon; irritable colon).
- Ulcus duodeni (duodenal ulcer)
- Ulcus ventriculi (gastric ulcer)
Musculoskeletal system and connective tissue (M00-M99)
- Osteoporosis (bone loss)
- Back and neck pain
Ears – mastoid process (H60-H95)
- Hearing loss
- Tinnitus (ringing in the ears)
- Vertigo (Scnwindel)
Psyche – nervous system (F00-F99; G00-G99)
- Alcohol dependence
- Bruxism (teeth grinding)
- Burnout syndrome
- Cephalgia (headache), unspecified
- Depression
- Infertility (infertility)
- Insomnia (sleep disorders)
- Mild cognitive impairment (“MCI”).
- Elevated morning serum cortisol levels are associated with decreased brain performance (concerning cognition, attention, memory, and visual organization) and reduced cerebral volume (especially parietal and frontal lobes)
- Libido disorders/libido loss
- Migraine
- Orgasm disorder
- Somatoform disorders (form of mental illness that leads to physical symptoms without the need to collect physical findings) – especially functional pain syndromes, especially cephalgia (headache).
- Tension headache
- Tobacco addiction
Pregnancy, childbirth and puerperium (O00-O99)
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Cephalgia (headache)
- Pyrosis (heartburn)
- Subclinical inflammation (synonyms: chronic subclinical inflammation; English “silent inflammation”, “silent (smouldering) inflammation”); chronic stress leads to depletion of the pituitary-hypothalamic-adrenal axis (HHN axis).
- Xerostomia (dry mouth).
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99).
- Libido disorder (male, female)
- Prostatitis (inflammation of the prostate)
- Sterility, erectile dysfunction (ED), impotence.
- Vaginismus (vaginismus)
- Cycle disorders of the woman
Injuries, poisonings and other consequences of external causes (S00-T98).
- Sick-building syndrome (synonyms: building-illness syndrome; SBS).
- Multiple Chemical Sensitivity (synonyms: chemical intolerance; multiple chemical sensitivity; idiopathic environmental intolerances (IEI); idiopathic chemical sensitivity; MCS; MCS syndrome; multiple chemical intolerance).
Further
- Accelerated aging process of immune cells
- Diabetogenic release of cortisol
- Influence on brain maturation
- In early childhood, there is faster maturation in the hippocampus and another part of the prefrontal cortex during adolescence (fits with theories of evolutionary biology)
- During adolescence, such as low standing in school, there is slower maturation in the previously mentioned region
- Limited performance
- Compensatory mechanisms such as unhealthy diet, alcohol and smoking.
- Poorer bone healing
- Increase in blood pressure
- Unfavorable course of chronic disease, especially tumor diseases.
- Shortened telomere length
Prognostic factors
- Disease of type 2 diabetes or condition after myocardial infarction (heart attack) or apoplexy (stroke) → mortality rate (death rate) ↑:
- Men with cardiometabolic disease and increased “job strain” (high job demands contrasted with low design opportunity): 149.8 per 10,000 person-years versus men without cardiometabolic disease: 97.7 per 10,000 person-years.
- Men without cardiometabolic disease and women (with or without cardiometabolic disease): “Job Strain” did not result in increased mortality.
