Pathogenesis (development of disease)
Glossitis can occur in the context of many diseases but also due to local causes.
Etiology (causes)
Biographic causes
- Hormonal factors – menopause (menopause).
Behavioral causes
- Nutrition
- Spices (in the sense of chemical irritation).
- Vital substance deficiency – vitamin A, C, respectively, iron deficiency anemia (iron), pernicious anemia (vitamin B12; folic acid).
- Consumption of stimulants (in the sense of chemical irritation).
- Alcohol
- Tobacco (smoking)
Disease-related causes
Blood, blood-forming organs – immune system (D50-D90).
- Iron deficiency anemia
- Immunodeficiency (immune deficiency), unspecified.
- Pernicious anemia – anemia caused by a deficiency of vitamin B12 or, less commonly, folic acid deficiency.
Endocrine, nutritional and metabolic diseases (E00-E90).
- Diabetes mellitus (diabetes).
- Menopause (menopause in women)
Infectious and parasitic diseases (A00-B99).
- Bacterial infections, unspecified
- Oral thrush – fungal infection of the oral cavity.
Mouth, esophagus (food pipe), stomach and intestines (K00-K67; K90-K93).
- Tartar
Musculoskeletal system and connective tissue (M00-M99)
- Sjögren’s syndrome (group of sicca syndromes) – autoimmune disease from the group of collagenoses, resulting in a chronic inflammatory disease of the exocrine glands, most commonly the salivary and lacrimal glands; typical sequelae or complications of sicca syndrome are:
- Keratoconjunctivitis sicca (dry eye syndrome) due to lack of wetting of the cornea and conjunctiva with tear fluid.
- Increased susceptibility to caries due to xerostomia (dry mouth) due to reduced salivary secretion.
- Rhinitis sicca (dry nasal mucous membranes), hoarseness and chronic cough irritation and impaired sexual function due to disruption of mucous gland production of the respiratory tract and genital organs.
Psyche – nervous system (F00-F99; G00-G99).
- Depression
- Psychogenic
Injuries, poisonings and other consequences of external causes (S00-T98).
- Allergic reaction, v.a.
- Food
- Dental fillings
- Dentures
- Injuries to the tongue caused by dentures, tooth edges, etc.
Laboratory diagnoses – laboratory parameters that are considered independent risk factors.
- Iron deficiency
- Folic acid deficiency
- Vitamin A deficiency
- Vitamin B12 deficiency
- Vitamin C deficiency
Medication
- Lisinopril (ACE inhibitor)