Tramadol – what the active ingredient can do

How tramadol works Tramadol is a pain-relieving (analgesic) substance from the opioid group. Humans have an endogenous analgesic system that is activated in stressful situations, among other things. For example, after serious accidents, injured people are often initially able to help others without even noticing their own injury. In addition, the analgesic prevents the reuptake … Tramadol – what the active ingredient can do

What is a Placebo?

In 1955, American physician Henry Beecher published observations he had made on U.S. soldiers during World War II in his book “The Powerful Placebo.” To relieve pain in these, he administered morphine. When he ran out, he replaced it with weak saline, with the effect that the “ineffective” substance relieved the pain of many soldiers. … What is a Placebo?

Zuclopenthixol

Products Zuclopenthixol is commercially available in the form of dragées, as drops, and as a solution for injection (Clopixol). It has been approved in many countries since 1977. Structure and properties Zuclopenthixol (C22H25ClN2OS, Mr = 400.7 g/mol) is present in drugs as zuclopenthixol dihydrochloride, zuclopenthixol acetate, or zuclopenthixol decanoate. Zuclopenthixol decanoate is a yellow, viscous, … Zuclopenthixol

Zoledronic Acid

Products Zoledronic acid is commercially available as an infusion preparation (Zometa, Aclasta, generics). It has been approved in many countries since 2000. Structure and properties Zoledronic acid (C5H10N2O7P2, Mr = 272.1 g/mol) is present in drugs as zoledronic acid monohydrate, a white crystalline powder that is sparingly soluble in water. It is an imidazole derivative … Zoledronic Acid

Zolmitriptan

Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan

Zolpidem

Products Zolpidem is commercially available as film-coated tablets, sustained-release tablets, and effervescent tablets (Stilnox, Stilnox CR, generics, USA: Ambien). It has been approved in many countries since 1990. Structure and properties Zolpidem (C19H21N3O, Mr = 307.39 g/mol) is an imidazopyridine that is structurally distinct from the benzodiazepines. It is present in drugs as zolpidem tartrate, … Zolpidem

Zonisamide

Products Zonisamide is commercially available in the form of capsules (Zonegran). It has been approved in many countries since 2006. Structure and properties Zonisamide (C8H8N2O3S, Mr = 212.2 g/mol) is a benzisoxazole derivative and a sulfonamide. It exists as a white powder that is soluble in water. Effects Zonisamide (ATC N03AX15) has anticonvulsant and antiepileptic … Zonisamide

Zopiclone

Products Zopiclone is commercially available in tablet form (Imovane, auto-generics). It has been approved in many countries since 1993. In the United States, the pure -enantiomer eszopiclone is also available (Lunesta). Structure and properties Zopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is a racemate and belongs to the cyclopyrrolones. It exists as a white to slightly … Zopiclone

Zinc

Products Zinc is found in numerous pharmaceutical products. This article refers to peroral administration, for example, in the form of tablets, chewable tablets, lozenges, and effervescent tablets. Zinc should not be confused with tin. Structure and properties Zinc (Zn) is a chemical element with an atomic number of 20 that exists as a brittle, blue-silver … Zinc

Zinc Oil

Products Zinc oil is prepared in pharmacies. In some countries, ready-made products are on sale. Production Zinc oil is a suspension of zinc oxide in olive oil. 100 g of zinc oil is prepared as follows: 50.0 g zinc oxide 50.0 g olive oil The zinc oxide is sieved (300) and added to the olive … Zinc Oil

Zinc Pyrithione

Products Zinc pyrithione is commercially available as a shampoo (Squa-med). It has been approved as a drug in many countries since 1980. In addition, cosmetics and medical products containing the active ingredient are also available. Structure and properties Zinc pyrithione (C10H8N2O2S2Zn, Mr = 317.7 g/mol) is structurally related to dipyrithione. Effects Zinc pyrithione (ATC D11AC08) … Zinc Pyrithione

Zinc Oxide

Products Zinc oxide is contained in zinc ointments, shaking mixtures, in sunscreens, skin care products, hemorrhoid ointments, baby care products, cosmetics and wound healing ointments, among others. Zinc oxide is also combined with other active ingredients in a fixed manner and traditionally numerous magistral formulations have been made with the active ingredient. Its medicinal use … Zinc Oxide