Products Mirabegron is commercially available in the form of sustained-release film-coated tablets (Betmiga, USA: Myrbetriq). It was approved in the US and EU in 2012 and in many countries in 2014. Mirabegron was the first agent from the beta3 agonist group to be approved for the treatment of irritable bladder. It was originally intended to … Mirabegron
Products Suxamethonium chloride is commercially available as a solution for injection (lysthenone, succinoline). It was introduced in the 1950s and has been approved in many countries since 1954. Suxamethonium chloride is also known as succinylcholine or succinylcholine chloride, especially in English. In jargon, it is also called Suxi or Sux. Structure and properties Suxamethonium chloride … Suxamethonium Chloride
Products Lofexidine was approved in the United States in 2018 in film-coated tablet form (Lucemyra). In the United Kingdom, the agent was approved for the treatment of opioid withdrawal back in the early 1990s (UK: BritLofex). Structure and properties Lofexidine (C11H12Cl2N2O, Mr = 259.1 g/mol) is present in the drug as lofexidine hydrochloride, a white … Lofexidine
Products Eluxadoline was approved in the form of film-coated tablets in the US in 2015, in the EU in 2016, and in many countries in 2018 (US: Viberzi, EU, CH: Truberzi). Structure and properties Eluxadoline (C32H35N5O5, Mr = 569.7 g/mol) Effects Eluxadoline (ATC A07DA06) has antidiarrheal and analgesic properties. It is an agonist at μ-opioid … Eluxadoline
Products Capsaicin cream at 0.025% or 0.075% (also 0.1%) is not registered as a finished drug in many countries, unlike other countries. It is produced as an extemporaneous preparation in pharmacies. The specialized trade can also order them from specialized service providers. On the other hand, patches containing the active ingredient (Qutenza) are approved as … Capsaicin Cream
Products Capsaicin is commercially available in many countries as creams and patches, among other products. Capsaicin cream at 0.025% and 0.075% is not commercially available as a finished drug product. It is produced as a magisterial formulation in pharmacies. See also under the article capsaicin cream. Structure and properties Capsaicin (C18H27NO3, Mr = 305.4 g/mol) … Capsaicin
Products Hydromorphone is commercially available as sustained-release tablets, sustained-release capsules, capsules, solution for injection, solution for infusion, and drops (e.g., Palladon, Jurnista, Hydromorphoni HCl Streuli). It has been approved in many countries since 1996. Structure and properties Hydromorphone (C17H19NO3, Mr = 285.3 g/mol) is a semisynthetic, hydrogenated and oxidized morphine derivative. It is present in … Hydromorphone
Products In many countries, there are currently no medicines approved that contain only cannabidiol. However, the active ingredient is a component of the cannabis oral spray Sativex, which is registered as a drug for MS treatment in many countries and also contains THC. The oral solution Epidiolex or Epidyolex was approved as a drug in … Cannabidiol
Products Hemp with a high content of cannabidiol and a low total content of tetrahydrocannabinol (less than 1%) can be legally sold in many countries since 2016 and is available from specialized suppliers and web stores. Cannabidiol hemp is approved as a tobacco substitute product and not yet as a medicine. Neither cannabidiol nor cannabidiol … Cannabidiol Hemp
Products Nalmefene is commercially available in the form of film-coated tablets (Selincro). It was registered in many countries in 2014. Structure and properties Nalmefene (C21H25NO3, Mr = 339.4 g/mol) is structurally closely related to naltrexone, from which it is derived. In the drug product, it is present as nalmefene hydrochloride and dihydrate, a white crystalline … Nalmefene
There are about 650 muscles in the human body. These fulfill different tasks. One part of them is responsible for the movements we perform with arms, legs and other parts of the body. The muscles of our extremities are important for this. Another part takes over the supporting function and makes sure that we do … Muscle Agonist Antagonist
Synergist A synergist is the muscle that performs the same function as the agonist. Often there are several synergists, which all work together. For example, when the arm is bent, there are other muscles besides the biceps that can trigger a flexion. The interaction of all these muscles ultimately leads to the final movement in … Synergist | Muscle Agonist Antagonist
