Products Antazoline is fixed combination with tetryzoline in the form of eye drops commercially available (Spersallerg, Spersallerg SDU). It has been approved in many countries since 1967. Structure and properties Antazoline (C17H19N3, Mr = 265.35 g/mol) is present in drugs as antazoline hydrochloride, a white crystalline powder that is sparingly soluble in water. It is … Antazoline: Antihistamine
Products Gefitinib is commercially available in the form of film-coated tablets (Iressa). It was approved in many countries in 2011. Structure Gefitinib (C22H24ClFN4O3, Mr = 446.9 g/mol) is a morpholine and aniline quinazoline derivative. It exists as a white powder that is sparingly soluble in water, especially at high pH. Effects Gefitinib (ATC L01XE02) is … Gefitinib
Products No medicines containing clonixin are approved in many countries, but other NSAIDs are available that can be used as substitutes. Clonix 300 mg capsules are available in Portugal. Structure and properties Clonixin (C13H11ClN2O2, Mr = 262.7 g/mol) is a derivative of nicotinic acid and aniline. It is structurally related to other NSAIDs. Effects Clonixin … Clonixin
Products Bromhexine is commercially available as tablets, syrup, and solution (Bisolvon). It has been approved in many countries since 1966. Structure and properties Bromhexine (C14H20Br2N2, Mr = 376.1 g/mol) is a brominated aniline and benzylamine derivative. It is present in drugs as bromhexine hydrochloride, a white crystalline powder that is very sparingly soluble in water. … Bromhexine
Products Erlotinib is commercially available in the form of film-coated tablets (Tarceva). It has been approved in many countries since 2005. Generic versions were registered in 2018. Structure and properties Erlotinib (C22H23N3O4, Mr = 393.4 g/mol) is present in drugs as erlotinib hydrochloride, a white powder that is sparingly soluble in water. Solubility increases with … Erlotinib
Products No drugs containing acetanilide are approved in many countries. Antifebrin is no longer on the market. Acetanilide was among the first synthetic analgesics. It was synthesized in the 19th century. Its pharmacological properties were accidentally discovered in the late 1880s. Structure and properties Acetanilide (C8H9NO, Mr = 135.3 g/mol) exists as a white, odorless, … Acetanilide
Products Osimertinib was approved in the United States in 2015 and in the EU and Switzerland in 2016 in film-coated tablet form (Tagrisso). Structure and properties Osimertinib exists in the drug product as osimertinib mesilate (C28H33N7O2 – CH4O3S, Mr = 596 g/mol). It is a methylindole, aniline and pyrimidine derivative. Effects Osimertinib (ATC L01XE35) has … Osimertinib
Definition The best-known representative of the aromatics is benzene (benzenes), which consists of six carbon atoms arranged in a ring with angles of 120°. Benzene is usually drawn like a cylcoalkene, each with three alternating single and double bonds. However, benzene and the other aromatics do not belong to the alkenes and behave chemically differently. … Aromatics
Products Afatinib was approved in the US and EU in 2013 and in many countries in 2014 in film-coated tablet form (Giotrif). Structure and properties Afatinib (C24H25ClFN5O3, Mr = 485.9 g/mol) is a 4-aniline quinazoline derivative that is present in drugs as afatinib dimaleate, a white to brownish-yellow powder that is soluble in water. It … Afatinib
