Postisometric Relaxation

Postisometric Relaxation (PIR) is a physiotherapeutic technique to relax reflectorically tense muscles. After a trauma, i.e. an injury, but also after an operation, our muscles want to protect the affected area by increasing their tone, i.e. their tension, and by reducing their ability to move in the affected area. It is often important to ensure … Postisometric Relaxation

Azilsartan

Products Azilsartan has been approved in the United States and the EU in tablet form since 2011 (Edarbi). In many countries, it was registered in August 2012 as the 8th member of the sartan drug group. In 2014, a fixed combination with chlortalidone was approved (Edarbyclor). Structure Azilsartan (C25H20N4O5, Mr = 456.5 g/mol) is present … Azilsartan

Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses

Revefenacin

Products Revefenacin was approved in the United States in 2018 as a monodose inhalation solution (Yupelri). The active ingredient belongs to the LAMA group. Structure and properties Revefenacin (C35H43N5O4, Mr = 597.8 g/mol) exists as a white crystalline powder and is sparingly soluble in water. It has an active metabolite formed by hydrolysis. Effects Revefenacin … Revefenacin

Suvorexant

Products Suvorexant was approved in the United States in 2014 as the first agent in the orexin receptor antagonist group in the form of film-coated tablets (Belsomra). Structure and properties Suvorexant (C23H23ClN6O2, Mr = 450.9 g/mol) exists as a white powder that is insoluble in water. It is a benzoxazole, diazepane and triazole derivative. Effects … Suvorexant

Netupitant, Palonosetron

Products The fixed combination of netupitant and palonosetron has been approved in capsule form (Akynzeo). The drug was released in many countries in 2015. Structure and properties Netupitant (C30H32F6N4O, Mr = 578.6 g/mol) is a fluorinated piperazine and pyrimidine derivative. Palonosetron (C19H24N2O, Mr = 296.4 g/mol) is present in drugs as palonosetron hydrochloride, a white … Netupitant, Palonosetron

Lysine

Products Lysine is commercially available as a monopreparation from Burgerstein, among others, in the form of tablets. Structure and properties Lysine (C6H14N2O2, Mr = 146.2 g/mol) is a natural and essential amino acid found in proteins and, for example, in meat. Essential means that the body must take it in with food and does not … Lysine

Propiverine

Products Propiverine was approved in many countries in 2020 in the form of modified-release hard capsules (Mictonorm). Later, coated tablets were also registered (Mictonet). This is an older active ingredient that was available earlier in Germany, for example. Structure and properties Propiverine (C23H29NO3, Mr = 367.5 g/mol) is present in drugs as propiverine hydrochloride. Active … Propiverine

Caffeine Withdrawal

Symptoms Possible symptoms of caffeine withdrawal in dependent individuals include: Headache Fatigue, drowsiness, weakness, low energy. Attention and concentration disorders, drowsiness. Dissatisfaction, disgruntlement Irritability Flu-like symptoms, muscle pain Changes in blood pressure, rapid heartbeat Nausea, vomiting, constipation. The discomfort may occur a few hours after caffeine abstinence and last a few to several days. Causes … Caffeine Withdrawal

Olmesartan

Products Olmesartan is commercially available in the form of film-coated tablets (Olmetec, Votum, fixed combinations with amlodipine and hydrochlorothiazide). It has been approved in many countries since 2005. Generics were registered in 2016 and went on sale in 2017. Structure and properties Olmesartan is present in drugs as olmesartan medoxomil (C29H30N6O6, Mr = 558.6 g/mol), … Olmesartan