Products Eluxadoline was approved in the form of film-coated tablets in the US in 2015, in the EU in 2016, and in many countries in 2018 (US: Viberzi, EU, CH: Truberzi). Structure and properties Eluxadoline (C32H35N5O5, Mr = 569.7 g/mol) Effects Eluxadoline (ATC A07DA06) has antidiarrheal and analgesic properties. It is an agonist at μ-opioid … Eluxadoline
Products Alfuzosin is commercially available in sustained-release tablet form and has been approved in many countries since 1994. In addition to the original Xatral, generic versions are also available. Structure and properties Alfuzosin (C19H27N5O4, Mr = 389.45 g/mol) is a quinazoline derivative. It is present in drugs as alfuzosin hydrochloride, a white crystalline powder that … Alfuzosin
Products Clozapine is commercially available in tablet form (Leponex, generic). It has been approved in many countries since 1972. It is also known as Clozaril in some countries. Clozapine was developed at Wander and Sandoz. Structure and properties Clozapine (C18H19ClN4, Mr = 326.8 g/mol) exists as a yellow crystalline powder that is practically insoluble in … Clozapine
Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron
Products Hydromorphone is commercially available as sustained-release tablets, sustained-release capsules, capsules, solution for injection, solution for infusion, and drops (e.g., Palladon, Jurnista, Hydromorphoni HCl Streuli). It has been approved in many countries since 1996. Structure and properties Hydromorphone (C17H19NO3, Mr = 285.3 g/mol) is a semisynthetic, hydrogenated and oxidized morphine derivative. It is present in … Hydromorphone
Products Pegvisomant is commercially available as a powder and solvent for the preparation of a solution for injection (Somavert). It has been approved in many countries since 2005. Structure and properties Pegvisomant is a derivative of human growth hormone produced by biotechnological methods. It consists of 191 amino acids and is pegylated at several sites. … Pegvisomant
Products Naloxegol is commercially available in the form of film-coated tablets (Moventig, USA: Movantik). It was approved in many countries in 2015. Structure and properties Naloxegol (C34H53NO11, Mr = 651.8 g/mol) is a pegylated derivative of naloxone. It exists as naloxegoloxalate, a white powder that is highly soluble in water. Effects Naloxegol (ATC A06AH03) is … Naloxegol
Products Agomelatine is commercially available in the form of film-coated tablets (Valdoxan, generic). It was approved in the EU in 2009 and in many countries in 2010. Structure and properties Agomelatine (C15H17NO2, Mr = 243.30 g/mol) exists as a white powder that is practically insoluble in water. It is a naphthalene analog of the epiphyseal … Agomelatine
Products Stimulants are commercially available as drugs, narcotics, dietary supplements, and foods. Dosage forms include tablets, capsules, and solutions. Structure and properties Stimulants do not have a uniform chemical structure, but groups can be identified. Many, for example the amphetamines, are derived from the natural catecholamines such as epinephrine and norepinephrine. Effects The active ingredients … Stimulants
Products Fexofenadine is commercially available in tablet form (Telfast, Telfastin Allergo, generic). It was approved in many countries in 1997 and has been available without a doctor’s prescription since 2010. Telfastin Allergo 120 for self-medication went on sale in February 2011. Fexofenadine is the successor product to terfenadine (Teldane), which had to be withdrawn from … Fexofenadine
There are about 650 muscles in the human body. These fulfill different tasks. One part of them is responsible for the movements we perform with arms, legs and other parts of the body. The muscles of our extremities are important for this. Another part takes over the supporting function and makes sure that we do … Muscle Agonist Antagonist
Synergist A synergist is the muscle that performs the same function as the agonist. Often there are several synergists, which all work together. For example, when the arm is bent, there are other muscles besides the biceps that can trigger a flexion. The interaction of all these muscles ultimately leads to the final movement in … Synergist | Muscle Agonist Antagonist
