Terbutaline

Products Terbutaline is commercially available as a turbuhaler and has been approved in many countries since 1987 (Bricanyl). The syrup is out of commerce. Other dosage forms are available in other countries (e.g., tablets, solution for injection). Structure and properties Terbutaline (C12H19NO3, Mr = 225.3 g/mol) is present in drugs as terbutaline sulfate, a white … Terbutaline

Testosterone Effects

Products Testosterone is commercially available as a drug product including transdermal gel, transdermal patch, transdermal solution, and injectable. In some countries, other dosage forms such as buccal tablets are available. Andriol Testocaps capsules have been discontinued in many countries since 2020. Structure and properties Testosterone (C19H28O2, Mr = 288.4 g/mol) is a steroid. It exists … Testosterone Effects

Chronic Venous Insufficiency

Symptoms In venous insufficiency, the normal return flow of venous blood to the heart is disturbed due to various causes. The following symptoms occur on the legs, especially the ankle and lower leg: Superficial venous dilatation: Varicose veins, spider veins, varicose veins. Pain and heaviness, tired legs Fluid retention, swelling, “water in the legs”. Calf … Chronic Venous Insufficiency

Hepatosis: Causes, Symptoms & Treatment

Hepatosis is damage to the liver that results from a back-up of bile. This causes the bile ducts to swell, leading to other symptoms such as jaundice. The causes can be manifold. Often, drug treatment responds well. What is hepatosis? By hepatosis, physicians mean an allergic-toxic reaction of the bile that leads to subsequent damage … Hepatosis: Causes, Symptoms & Treatment

Etilefrin

Products Etilefrin is commercially available in drop form (Effortil) and has been approved in many countries since 1958. The combination with dihydroergotamine (Effortil plus) is no longer marketed. Structure and properties Etilefrin (C10H15NO2, Mr = 181.23 g/mol) is a racemate and is present in drugs as etilefrine hydrochloride, a white crystalline powder or colorless crystals … Etilefrin

Loop Diuretics

Products Loop diuretics are commercially available as tablets, sustained-release capsules, and injection and infusion preparations. Torasemide and furosemide are the most commonly used in many countries today. Structure and properties Available loop diuretics are usually sulfonamide or sulfonylurea derivatives. Representatives without a sulfonamide structure also exist, for example, the phenoxyacetic acid derivative etacrynic acid. Effects … Loop Diuretics

Diazoxide

Products Diazoxide is commercially available in capsule form (Proglicem). It has been approved in many countries since 1978. Structure and properties Diazoxide (C8H7ClN2O2S, Mr = 230.7 g/mol) exists as a white powder that is practically insoluble in water. It is a benzothiadiazine derivative and structurally related to the thiazides, but is not diuretic. Effects Diazoxide … Diazoxide

Hirsutism: Excessive Hair Growth

Definition Increased body and facial hair in women corresponding to the male hair type due to androgen-induced conversion of vellus hair to terminal hair. Symptoms Excessive and altered hair growth (thick and pigmented) on the face, chest, abdomen, legs, buttocks, and back Acne Deeper voice Increased muscle mass Decrease in breast size Androgenetic alopecia Views … Hirsutism: Excessive Hair Growth

Levofloxacin

Products Levofloxacin is commercially available as film-coated tablets and as an infusion solution (Tavanic, generic). It was approved in many countries in 1998. Generics came on the market in 2011. In 2018, a solution for a nebulizer was registered (Quinsair). The racemate ofloxacin is available as tablets (Tarivid), eye drops, and eye ointment (Floxal). Structure … Levofloxacin

Salbutamol: Drug Effects, Side Effects, Dosage and Uses

Products Salbutamol is commercially available as a metered-dose inhaler, inhalation solution, diskus, syrup, infusion concentrate, and solution for injection (Ventolin, generics). It has been approved in many countries since 1972 and is also known as albuterol in English-speaking countries. Salbutamol is the precursor of salmeterol and vilanterol (all GlaxoSmithKline). Structure and properties Salbutamol (C13H21NO3, Mr … Salbutamol: Drug Effects, Side Effects, Dosage and Uses

Alpha-Glucosidase Inhibitors

Effects Alpha-glucosidase inhibitors (ATC A10BF) have antidiabetic properties: Glucose is released more slowly in the gut and absorbed more slowly into the blood Decrease the rise in blood glucose after meals and blood sugar fluctuations. Do not cause hypoglycemia as monotherapy Mechanism of action The action is based on the inhibition of intestinal enzymes (alpha-glucosidases) … Alpha-Glucosidase Inhibitors