Human Insulin

Products Human insulin is commercially available as an injectable (e.g., Huminsulin, Insuman). Rapid-acting and sustained-release dosage forms exist (e.g., isophane insulin), as well as mixed insulins. Human insulin is produced by biotechnological methods and stored in a refrigerator. It should not be frozen or exposed to high heat. Some preparations can be stored with the … Human Insulin

Remogliflozin

Structure and properties Remogliflozin (C23H32N2O8, Mr = 464.5 g/mol) is present in drugs as remogliflozinetabonate, an ester prodrug of remogliflozin. Effects Remogliflozin has antidiabetic and antihyperglycemic properties. It is a selective inhibitor of sodium–glucose co-transporter 2 (SGLT2). This transporter is responsible for the reabsorption of glucose at the proximal tubule of the nephron. Inhibition leads … Remogliflozin

Biguanide

Active ingredients Metformin (Glucophage, generics, combination products) Detailed information. Buformin (off label) Phenformin (out of trade)

Gestational Diabetes

Symptoms Gestational diabetes is a glucose intolerance that is first discovered during pregnancy and is common, occurring in approximately 1-14% of all pregnancies. Typical symptoms of diabetes mellitus such as thirst, frequent urination, and fatigue may occur, but are considered rare. Nonspecific complaints such as increased susceptibility to urinary tract infections may indicate gestational diabetes. … Gestational Diabetes

Porcine Insulin

Products Porcine insulin was commercially available as an injectable (insulin hypurin porcine). It was available as rapid-acting insulin, isophane insulin, and mixed insulin. Porcine insulin is stored in a refrigerator. It should not be frozen or exposed to high heat. Insulin Hypurin Porcine was withdrawn from the market in many countries on October 31, 2015. … Porcine Insulin

NSAID

Products Nonsteroidal anti-inflammatory drugs (NSAIDs) are available in numerous dosage forms. These include film-coated tablets, tablets, sustained-release tablets, oral suspensions, oral granules, suppositories, NSAID eye drops, lozenges, emulsifying gels, and creams (selection). The first active ingredient from this group was salicylic acid, which was used medicinally in the 19th century in the form of the … NSAID

Rosiglitazone

Products Rosiglitazone was commercially available in tablet form (Avandia). It had been approved since 1999 and was also commercially available in fixed combination with the biguanide metformin (Avandamet). The combination with the sulfonylurea glimepiride (Avaglim, EU, off-label) was not approved in many countries. A publication in on possible cardiovascular risks led to a controversy about … Rosiglitazone

Benazepril

Products Benazepril was commercially available as film-coated tablets (Cibacen, off label). It was also available as a fixed-dose combination with hydrochlorothiazide (Cibadrex, off label). Benazepril was approved in many countries beginning in 1990. Structure and properties Benazepril (C24H28N2O5, Mr = 424.5 g/mol) is present in drugs as benazepril hydrochloride, a white crystalline powder that is … Benazepril

Chlorpropamide

Products Chlorpropamide was commercially available in many countries in tablet form as a fixed combination with metformin (Diabiformin). The drug was approved in 1971 and is no longer available. Structure and properties Chlorpropamide (C10H13ClN2O3S, 276.74 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Chlorpropamide (ATC A10BB02) has antidiabetic properties. Indications … Chlorpropamide

Celiprolol

Products Celiprolol is commercially available in the form of film-coated tablets (Selectol). It has been approved in many countries since 1987. Structure and properties Celiprolol (C20H34ClN3O4, Mr = 415.95 g/mol is a racemate and is present in drugs as celiprolol hydrochloride, a white to pale yellow crystalline powder that is readily soluble in water. Effects … Celiprolol