Products Oxfendazole is commercially available as a suspension and bolus. It has been approved in many countries since 1980. Structure and properties Oxfendazole (C15H13N3O3S, Mr = 315.3 g/mol) is a benzimidazole derivative. Effects Oxfendazole (ATCvet QP52AC02) has antihelminthic properties. Indications Oxfendazole is used in cattle and sheep for the treatment of worm infections.
Products Oxibendazole is commercially available as an oral paste (Equitac). It has been approved in many countries since 1988. Structure and properties Oxibendazole (C12H15N3O3, Mr = 249.3 g/mol) is a benzimidazole derivative. Effects Oxibendazole (ATCvet QP52AC07) is antihelminthic. Indications For treatment of worm infestation in horses and ponies (nematodes, ).
Products Pyrvinium is commercially available as an oral suspension and in the form of dragées. It is no longer available in many countries. Structure and properties Pyrvinium (C26H28N3+, Mr = 382.5 g/mol) is present in pharmaceuticals as pyrvinium embonate or pyrvinium pamoate. Pyrvinium embonate is an orange-red to orange-brown powder with almost no odor and … Pyrvinium
Symptoms The infection is usually asymptomatic. Transient pulmonary symptoms such as cough, dyspnea, asthma-like symptoms, Löffler syndrome with eosinophilic pulmonary infiltrates occur. The pulmonary symptoms are the result of the larvae migrating into the lungs. Other symptoms include fever, abdominal pain, nausea, and vomiting. Worm eggs are first found in the stool 7-9 weeks after … Roundworm (Ascaris Lumbricoides)
Products Various veterinary drugs containing praziquantel are on the market in many countries. In contrast, no human drugs are registered. Human drugs are also available in Germany, the United States, and other countries, such as Biltricide film-coated tablets. Structure and properties Praziquantel (C19H24N2O2, Mr = 312.4 g/mol) is a racemate. It exists as a white … Praziquantel
Products Febantel is commercially available in combination tablet and suspension form as a veterinary drug. It has been approved in many countries since 1988. Structure and properties Febantel (C20H22N4O6S, Mr = 446.5 g/mol) is a sample zimidazole and a guanidine derivative. It exists as a colorless powder and is insoluble in water and alcohol due … Febantel
Products Fenbendazole is commercially available as granules, paste, powder, bolus, suspension, and tablets, among others. It has been approved in many countries since 1976. Structure and properties Fenbendazole (C15H13N3O2S, Mr = 299.3 g/mol) is a benzimidazole derivative. It exists as a white powder that is practically insoluble in water. Effects Fenbendazole (ATCvet QP52AC13) has antihelminthic … Fenbendazole
Products Emodepside is commercially available in combination with praziquantel in tablet form and as a spot-on preparation. It has been approved in many countries since 2005. Effects Emodepside (ATCvet QP52AA51) has antihelminthic properties. Indications For the treatment of infestation with worms in dogs and cats.
Single administration Many medications are administered daily over a long period of time, such as agents for high blood pressure or lipid-lowering agents such as statins for disorders of lipid metabolism. However, various drugs also exist for which a single dose, i.e., a single administration, is sufficient. If necessary, it can be repeated after a … Single Dose
Products In Germany, niclosamide is commercially available in the form of chewable tablets (Yomesan). In many countries, the drug is not registered. Structure and properties Niclosamide (C13H8Cl2N2O4, Mr = 327.1 g/mol) is a chlorinated and nitrated benzamide and salicylic acid derivative. It exists as yellowish white to yellowish fine crystals and is practically insoluble in … Niclosamide
Products Epsiprantel is commercially available as a veterinary drug in the form of film-coated tablets. It has been approved in many countries since 1996. Structure and properties Epsiprantel (C20H26N2O2, Mr = 326.4 g/mol) is a piperazine derivative. Effects Epsiprantel (ATC QP52AA04) has antihelminthic activity against common tapeworms found in dogs and cats. Indications Treatment of … Epsiprantel
Products Monepantel is commercially available as a solution for administration as a veterinary drug. It has been approved in many countries since 2010. Structure and properties Effects Monepantel (ATCvet QP52AX09) is antihelminthic with a broad spectrum of activity. Indications For treatment of worm infections with nematodes in the digestive tract in sheep.