Symptoms Glaucoma is a progressive eye disease that is initially asymptomatic. Patients have no symptoms until the optic nerve becomes increasingly damaged, which can lead to irreversible visual impairment with visual field loss and blindness. Glaucoma represents the most common cause of blindness. Causes The cause of the disease is usually an increase in intraocular … Glaucoma: Causes and Treatment
Products Apraclonidine is commercially available in the form of eye drops (iopidine). It has been approved in many countries since 1995. Structure and properties Apraclonidine (C9H10Cl2N4, Mr = 245.1 g/mol) is an amino derivative of clonidine. It is present in the drug as apraclonidine hydrochloride, a white powder that is highly soluble in water. Effects … Apraclonidine
Products Brimonidine is commercially available in the form of eye drops (Alphagan, generic). It is also available in combination with timolol (Combigan, generic) and has been approved in many countries since 1998. The active ingredient is also used for the external treatment of rosacea, see under the article Brimonidine gel. Finally, brimonidine is also combined … Brimonidine
Products Mirvaso brimonidine gel was approved in the EU in 2013 and in many countries in 2014. Structure and properties Brimonidine (C11H10BrN5, Mr = 292.1 g/mol) is present in the drug as brimonidine tartrate, a white to yellow powder that is soluble in water. It has a similar structure to clonidine and apraclonidine. Effects Brimonidine … Brimonidine Gel
