Rosuvastatin

Products Rosuvastatin is commercially available in the form of film-coated tablets (Crestor, generic, auto-generic). It was approved in many countries in 2006 (Netherlands: 2002, EU and US: 2003). The marketing authorization holder is AstraZeneca. The statin was originally developed at Shionogi in Japan. In the USA, generic versions came on the market in 2016. In … Rosuvastatin

Sertindol

Products Sertindole is commercially available in the form of film-coated tablets (Serdolect). It has been approved in many countries since 1997. Structure and properties Sertindole (C24H26ClFN4O, Mr = 440.9 g/mol) was developed as the first neuroleptic with a phenylindole structure. Effects Sertindole (ATC N05AE03) has antipsychotic properties. The effects are due to antagonism at dopamine … Sertindol

Atorvastatin

Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin

Health Evaluation of Tea

Tea is becoming increasingly popular as a beverage. Not only because of the pleasure from the scent and aroma, you do something good with a cup of tea. Our health also benefits from the positive properties of tea leaves. This has been proven by numerous scientific studies in which the effects of the various substances … Health Evaluation of Tea

Tension-belt Osteosynthesis: Treatment, Effects & Risks

Tension-belt osteosynthesis is a surgical procedure for reduction and fixation of dislocated fractures that pass through joints. This is a commonly used and reliable method in surgical and orthopedic care. What is tension-belt osteosynthesis? Tension-belt osteosynthesis is a surgical procedure for reduction and fixation of dislocated fractures that pass through joints. It is used, for … Tension-belt Osteosynthesis: Treatment, Effects & Risks

Silodosin

Products Silodosin has been approved in hard capsule form in the United States since 2008, in the EU since 2010, and in many countries since 2016 (Urorec). Generic versions are registered in some countries. Structure and properties Silodosin (C25H32F3N3O4, Mr = 495.5) exists as a white to yellowish powder that is sparingly soluble in water. … Silodosin

Phenylpropanolamine

Products Phenylpropanolamine is no longer on the market as a human drug in many countries. It was formerly contained in Astho-Med Syrup, Contac, Dimetane, Dimetapp, and Slim Caps, among others. Structure and properties Phenylpropanolamine (C9H13NO, Mr = 151.21 g/mol) has a phenylethylamine structure and exists as a racemate. The salt phenylpropanolamine hydrochloride is a white … Phenylpropanolamine

Alpha Blocker

Products Alpha blockers are available in many countries in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. The most commonly prescribed today is tamsulosin (Pradif T, generic). Alpha blocker is short for alpha1-adrenoreceptor antagonist. Structure and properties The first alpha blockers-alfuzosin, doxazosin, and terazosin-were developed as derivatives of quinazoline: Effects Alpha blockers (ATC … Alpha Blocker

Sacubitril

Products The fixed combination of the neprilysin inhibitor sacubitril with valsartan was approved in the United States, the EU, and many countries in 2015 in the form of film-coated tablets (Entresto). The combination is also referred to as LCZ696. Structure and properties Sacubitril (C24H29NO5, Mr = 411.5 g/mol) is an ester prodrug that is hydrolyzed … Sacubitril

Hyposensitization: Treatment, Effects & Risks

Hyposensitization is a therapy that attempts to curb the effects of allergic diseases. Hyposensitization involves introducing small amounts of allergenic substances into the body. The goal of the treatment is that habituation to the allergy-causing substances occurs and the immune system‘s exaggerated reactions no longer occur. What is hyposensitization? Hyposensitization is a therapy that attempts … Hyposensitization: Treatment, Effects & Risks