Cefepime

Products Cefepime is commercially available as a powder for solution for injection or infusion (generic). It has been approved in many countries since 2007. Structure and properties Cefepime (C19H24N6O5S2, Mr = 480.6 g/mol) is present in drugs as cefepim dihydrochloride monohydrate, a white to yellowish powder that is readily soluble in water. Effects Cefepime (ATC … Cefepime

Cefixime

Products Cefixime was commercially available in tablet form (Cephoral). It had been approved in many countries since 1992. Structure and properties Cefixime (C16H15N5O7S2, Mr = 453.4 g/mol) is a white powder that is sparingly soluble in water. It is a semisynthetic cephalosporin. In medicinal products, it is anhydrous. Effects Cefixime (ATC J01DD08) is bactericidal against … Cefixime

Cefoperazone

Products Cefoperazone is commercially available as an oily suspension of mastitis. It has been approved in many countries since 1986. Structure and properties Cefoperazone (C25H27N9O8S2, Mr = 645.7 g/mol) Effects Cefoperazone (ATCvet QJ51DA32) has bactericidal properties. Indications For treatment of bacterial mastitis in cattle during lactation.

Cefotaxime

Products Injectables containing cefotaxime are no longer available in many countries Claforan is off the market. It was approved in 1981. Structure and properties Cefotaxime (C16H17N5O7S2, Mr = 455.5 g/mol) Effects Cefotaxime (ATC J01DA10) has bactericidal properties by inhibiting cell wall synthesis. Indications Bacterial infectious diseases

Cefovecin

Products Cefovecin is available as an injectable for animals. It has been approved in many countries since 2007. Structure and properties Cefovecin (C17H19N5O6S2, Mr = 453.5 g/mol) Effects Cefovecin (ATCvet QJ01DD91) has bactericidal properties with long-lasting activity against Gram-positive and Gram-negative bacteria. Indications For the treatment of bacterial infectious diseases in dogs and cats.

Cefpodoxime

Products Cefpodoxime is commercially available as film-coated tablets and as granules for preparation of a suspension (Podomexef, generics). It has been approved in many countries since 1991. Structure and properties Cefpodoxime (C15H17N5O6S2, Mr = 427.5 g/mol) is present in drugs as cefpodoxime proxetil. It is an ester prodrug and is rapidly converted to cefpodoxime in … Cefpodoxime

Cefprozil

Products Cefprozil was commercially available as film-coated tablets and as a suspension (Procef). It was approved in many countries in 1995 and is currently no longer available. Structure and properties Cefprozil (C18H19N3O5S, Mr = 389.4 g/mol) is present in drugs as cefprozil monohydrate, a white to yellowish powder that is sparingly soluble in water. Effects … Cefprozil

Cefquinom

Products Cefquinom is commercially available as an injectable for animals. It has been approved in many countries since 1996. Structure and properties Cefquinom (C23H24N6O5S2, Mr = 528.6 g/mol) Effects Cefquinom (ATCvet QJ01DE90) is bactericidal. Indications Bacterial infectious diseases in cattle, cows, horses, and swine.

Ceftarolinefosamil

Products Ceftarolinefosamil is commercially available as a powder for the preparation of a concentrate for an infusion solution (Zinforo). It has been approved in many countries since 2013. Structure and properties Ceftarolinefosamil (C22H21N8O8PS4, Mr = 684.7 g/mol) is present in drugs as ceftarolinefosamil monoacetate monohydrate, a yellowish-white powder. Ceftarolinefosamil is a prodrug that is enzymatically … Ceftarolinefosamil

Cephalosporins

Products Cephalosporins are commercially available in the form of film-coated tablets, oral suspensions, granules, and injection and infusion preparations, among others. The basis for the discovery of cephalosporins was the isolation of the mold by the physician Giuseppe Brotzu. He found the fungus in wastewater from Cagliari in Sardinia in 1945. At the University of … Cephalosporins

Bacterial Skin Infections

Definition Infections of the skin that can affect various skin layers but also skin appendages (hair, nails, sweat glands) and are caused mainly by staphylococci or streptococci. Symptoms Vary depending on the clinical picture. Common symptoms include itching, redness and general discoloration of the skin, swelling, scaling, crusting, and pus accumulation. Causes Staph infections: Folliculitis … Bacterial Skin Infections

Meningococcus

Symptoms Meningococcus can cause a life-threatening meningitis, called meningococcal meningitis, and blood poisoning, called meningococemia. The three typical symptoms of meningitis include fever, severe headache and neck stiffness. Other possible symptoms include nausea, vomiting, photophobia, and neurological disorders such as confusion. In infants and young children, symptoms may be absent or difficult to recognize. Sepsis … Meningococcus