Zinc Pyrithione

Products Zinc pyrithione is commercially available as a shampoo (Squa-med). It has been approved as a drug in many countries since 1980. In addition, cosmetics and medical products containing the active ingredient are also available. Structure and properties Zinc pyrithione (C10H8N2O2S2Zn, Mr = 317.7 g/mol) is structurally related to dipyrithione. Effects Zinc pyrithione (ATC D11AC08) … Zinc Pyrithione

Oxetacaine

Products Muthesa (out of commerce) Structure and properties Oxetacaine (C28H41N3O3, Mr = 467.6 g/mol) belongs to the amide-type local anesthetics. Effects Oxetacaine (ATC C05AD06) has local anesthetic properties. Indications Symptomatic relief ulcer, gastritis, and esophagitis.

Misuse of Cough Syrup

Cough syrup as an intoxicant Many antirritant cough syrups contain active ingredients that are psychoactive in high doses and can be abused as intoxicants. Substances include, for example: Opioids such as codeine, dihydrocodeine and ethylmorphine. NMDA antagonists: dextromethorphan Antihistamines such as diphenhydramine and oxomemazine. Phenothiazines: promethazine (out of commerce). Such drugs are unlike other drugs … Misuse of Cough Syrup

Statins

Products Most statins are commercially available in the form of film-coated tablets, and some are also available as capsules. The first active ingredient to be marketed was lovastatin from Merck in the United States in 1987. In many countries, simvastatin (Zocor) and, shortly thereafter, pravastatin (Selipran) were the first agents to be approved in 1990. … Statins

Oxygen

Products Oxygen is commercially available in the form of compressed gas cylinders (oxygen cylinders) with a white color as a compressed gas. In many countries, it is available from PanGas, for example. Structure and properties Oxygen (symbol: O, elemental: O2, atomic number: 8, atomic mass: 15,999) is present as dioxygen (O2, O=O) as a colorless, … Oxygen

Propanol (Propan-1-Ol)

Products Propanol is available in pharmacies and drugstores. It is also known as propyl alcohol. The systematic name is propan-1-ol. Propanol should not be confused with the isomer isopropanol (propan-2-ol). Structure and properties Propanol (C3H8O, Mr = 60.1 g/mol) is a primary and linear alcohol. Formally, it is propane with a hydroxyl group at position … Propanol (Propan-1-Ol)

Moxidectin

Products Moxidectin is commercially available as a mono- and combination preparation as a solution, injection solution, oral gel, and spot-on preparation for animals. It has been approved in many countries since 1999. In 2018, a drug was approved in the U.S. for the treatment of onchocerciasis (river blindness). Structure and properties Moxidectin (C37H53NO8, Mr = … Moxidectin

Eteplirsen

Products Eteplirsen (Sarepta Therapeutics Inc) was approved in the United States in 2016 (Exondys 51). Structure and properties Eteplirsen (C364H569N177O122P30, Mr = 10305.7 g/mol) is a phosphorodiamidate morpholino oligomer (PMO) that binds selectively to exon 51 of pre-mRNA. It is an antisense oligomer with a high molecular weight. The sequence is complementary to the segment … Eteplirsen

Hima Pasta

Products Hima pasta was approved in many countries in 1995. After 22 years, in 2017, its sales were discontinued. Ingredients 1 g paste contained 10 mg zinc sulfate and 200 mg zinc oxide. Excipients: propylene glycol, dye E 172 (iron oxide), preservative benzalkonium chloride (selection). Effects The active ingredients zinc sulfate and zinc oxide have … Hima Pasta

Alum

Products Alum is found in deodorants and shaving pencils, among other products, and is available as an open commodity in pharmacies and drugstores. Structure and properties Alum in the pharmaceutical sense is aluminum potassium sulfate dodecahydrate (AlK(SO4)2 – 12H2O, Mr = 474.4 g/mol). Alum exists as a colorless, thirst-quenching crystalline mass or as a granular … Alum

Dithranol

Products Medicines containing dithranol are no longer on the market in many countries. They can be imported from abroad or prepared as extemporaneous preparations in a pharmacy. Corresponding regulations can be found, for example, in the DMS. Dithranol is incorporated into petrolatum and thick kerosene, for example. Structure Dithranol (C14H10O3, Mr = 226.2 g/mol) is … Dithranol