Symptoms The most common symptoms include cramping or dull abdominal pain. In addition, numerous other symptoms may occur, such as headache, menstrual migraine, back pain, pain in the legs, loss of appetite, nausea and vomiting, diarrhea, weakness, dizziness, flushing of the skin, flushing, sleep disturbances, mood swings, depression, irritability, and nervousness. The symptoms first appear … Menstrual Cramps
Products Parecoxib is commercially available in Germany as a powder for solution for injection (Dynastat). It is not approved in many countries. Structure and properties Parecoxib (C19H18N2O4S, Mr = 370.4 g/mol) is a prodrug of valdecoxib that is rapidly metabolized to the active drug in vivo. Effects Parecoxib (ATC M01AH04) is analgesic and anti-inflammatory. Its … Parecoxib
Products Celecoxib is commercially available in capsule form (Celebrex, generic). It was approved in many countries in 1999 as the first member of the selective COX-2 inhibitors. Generic versions went on sale in 2014. Structure and properties Celecoxib (C17H14F3N3O2S, Mr = 381.37 g/mol) is a benzenesulfonamide and a substituted diaryl pyrazole. It has a V-shaped … Celecoxib
Products Analgesics are available in numerous dosage forms. These include, for example, tablets, effervescent tablets, powders, granules, suppositories, syrups, transdermal patches, and injectables. One of the oldest painkillers is opium, which is obtained from the incised, immature capsules of the opium poppy. It has been used medicinally for thousands of years. The first synthetic analgesics, … Painkiller
Products Mavacoxib is commercially available in the form of chewable tablets for dogs (Trocoxil). It has been approved in many countries since 2009. Structure and properties Mavacoxib (C16H11F4N3O2S, Mr = 385.3 g/mol) is a pyrazole benzenesulfonamide that exists as a white to off-white powder. It is nearly insoluble in water at a pH between 1.2 … Mavacoxib
Products Ibuprofen is commercially available in the form of film-coated tablets, oral suspension, soft capsules, and granules, among others. It is also used externally as ibuprofen cream. Ibuprofen was developed in the 1960s at the Boots Pure Drug Company under the direction of Stewart Adams in Nottingham, England. It went on sale in the United … Ibuprofen: Drug Effects, Side Effects, Dosage and Uses
Products Robenacoxib is commercially available in tablet form and as a solution for injection for dogs and cats (Onsior). It has been approved in many countries since 2009. Structure and properties Robenacoxib (C16H13F4NO2, Mr = 327.3 g/mol) is structurally related to diclofenac. Effects Robenacoxib (ATCvet QM01AH91) has analgesic and anti-inflammatory properties. The effects are due … Robenacoxib
Products Rofecoxib was approved in many countries in 1999 in tablet and suspension form (Vioxx). It was withdrawn from the market again in late September 2004 because of adverse effects and is no longer available. Structure and properties Rofecoxib (C17H14O4S, Mr = 314.4 g/mol) is a methyl sulfone and a furanone derivative. It has a … Rofecoxib
Products Lumiracoxib (Prexige, Joicela, film-coated tablets) is no longer on the market or has not been approved in many countries because of its liver-toxic properties. The drug was not registered in many countries. Structure and properties Lumiracoxib (C15H13ClFNO2, Mr = 293.7 g/mol) is an analog of diclofenac (Voltaren) and belongs to the phenylacetic acid derivatives. … Lumiracoxib
