Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment
Symptoms The two leading symptoms of Sjögren’s syndrome (pronounced “Schögren”) are dry mouth and dry eyes with associated symptoms such as conjunctivitis, difficulty swallowing and speaking, gingivitis, and tooth decay. The nose, throat, skin, lips and vagina are also frequently dry. In addition, many other organs may be affected less frequently and include muscle and … Sjögren’s Syndrome: Causes and Treatment
Products Cyclophosphamide is commercially available in the form of dragées and as a dry substance for intravenous infusion (Endoxan). It has been approved in many countries since 1960. Structure and properties Cyclophosphamide (C7H15Cl2N2O2P, Mr = 261.1 g/mol) is a cytostatic drug belonging to the group of oxazaphosphorines, nitrogen-lost derivative. Effects Cyclophosphamide (ATC L01AA01) has cytotoxic … Cyclophosphamide
Chediak-Higashi syndrome (CHS) is an inherited disorder. Due to an immunodeficiency, the gene abnormality is associated with recurrent infections, peripheral neuropathy, and partial albinism. The life expectancy of affected individuals is greatly reduced. Bone marrow transplantation offers a chance of therapy. What is Chediak-Higashi syndrome? Chediak-Hygashi syndrome is a very rare autosomal recessive inherited disorder. … Chediak-Higashi Syndrome: Causes, Symptoms & Treatment
Linear IgA dermatosis is an autoimmunologic disease of the skin in which the body’s immune system produces autoantibodies against adhesion proteins. The result is blistering and reddening of the skin, which in individual cases may also affect the eye. If the eyes are involved, there is a risk of blindness, which may require invasive treatment … Linear IgA Dermatosis: Causes, Symptoms & Treatment
Products Mesna is commercially available as film-coated tablets and as a solution for injection (Uromitexan). It has been approved in many countries since 1981. Structure and properties Mesna (C 2 H 5 NaO 3 S 2 , M r = 164.2 g/mol) is a thiol compound. It exists as a white to pale yellow, crystalline, … Mesna
Bronchiolitis obliterans is a chronic disease of the bronchioles. It is progressive and eventually leads to obstruction of the bronchioles. At times, lung transplantation must be performed in the final stages of the disease. What is bronchiolitis obliterans? Bronchiolitis obliterans is characterized by inflammatory processes in the bronchioles that do not resolve. The bronchioles represent … Bronchiolitis Obliterans: Causes, Symptoms & Treatment
Products Bendamustine is commercially available as a lyophilizate for the preparation of an infusion solution (ribomustine). It actually has good oral bioavailability when taken fasting, but is only administered parenterally. Generic drugs are registered. Bendamustine was developed in 1963 by Ozegowski et al. in Jena in what was then East Germany and was marketed only … Bendamustine
Products Immunosuppressants are commercially available in numerous dosage forms, for example, as creams, ointments, tablets, capsules, solutions, eye drops, and injectables. Structure and properties Within immunosuppressants, several groups can be identified. These include steroids such as the glucocorticoids, substances of microbiological origin such as ciclosporin and mycophenolate mofetil, derivatives of nucleic acids and their components … Immunosuppressants
Epstein syndrome is the most severe form of MHY9-associated disease and, like all syndromes in the group, is caused by mutations in the MHY9 gene and is inherited in an autosomal dominant manner. The syndrome manifests as platelet deficiency, hearing loss, and inflammation of the kidneys. Treatment is symptomatic. What is Epstein syndrome? The disease … Epstein Syndrome: Causes, Symptoms & Treatment
Cyclophosphamide is a drug in the cytostatic drug class. It is used to treat cancer and to treat severe autoimmune diseases. What is cyclophosphamide? Cyclophosphamide is used to treat cancers and to treat severe autoimmune diseases. Cyclophosphamide is a drug with alkylating activity. Alkylating agents are chemical substances that can introduce alkyl groups into DNA. … Cyclophosphamide: Effects, Uses & Risks
Symptoms Lung cancer may initially be asymptomatic. It is often discovered only when it is no longer curable. Possible typical symptoms include a chronic cough, coughing up blood, difficulty breathing, recurrent colds, chest pain, and weakness, fatigue, lack of appetite, and weight loss. If spread further, additional symptoms include hoarseness, noises when breathing, and difficulty … Lung Cancer Causes and Treatment