Products Azithromycin is commercially available in the form of film-coated tablets, powder for preparation of a suspension, and granules (Zithromax, generic). Furthermore, a granule for the preparation of a sustained-release oral suspension is available (Zithromax Uno). Eye drops have also been released in some countries. Azithromycin has been approved in many countries since 1992. Structure … Azithromycin
Products The fresh or dried shiitake is available in grocery stores and specialty stores. It is one of the most widely consumed edible mushrooms in the world after the cultivated mushroom. Mushroom The shiitake mushroom is native to East Asia and has been cultivated for centuries – including in many countries today. In nature, it … Shiitake
Products Potassium is commercially available, among other things, in the form of effervescent tablets (so-called effervettes), as sustained-release dragées and sustained-release tablets (e.g., Kalium Hausmann, KCl-retard, Plus Kalium). It is also contained in sports drinks such as Isostar or Sponser. The dose is usually expressed in millimoles (mmol) or milliequivalents (mEq): 1 mmol = 39.1 … Potassium Health Benefits
Products Promazine is commercially available in the form of dragées (Prazine). It has been approved in many countries since 1957. Structure and properties Promazine (C17H20N2S, Mr = 284.4 g/mol) is present in drugs as promazine hydrochloride, a white crystalline powder that is very soluble in water. It is a dimethylamine derivative of phenothiazine and structurally … Promazine
Products Propiverine was approved in many countries in 2020 in the form of modified-release hard capsules (Mictonorm). Later, coated tablets were also registered (Mictonet). This is an older active ingredient that was available earlier in Germany, for example. Structure and properties Propiverine (C23H29NO3, Mr = 367.5 g/mol) is present in drugs as propiverine hydrochloride. Active … Propiverine
Products Coenzyme Q10 is commercially available as a dietary supplement in the form of capsules and drops, among other products. It is also found in cosmetics. As a drug, Q10 has not yet been registered in many countries. The short-chain analogue idebenone is approved as a drug. Structure and properties Coenzyme Q10 (C59H90O4, Mr = … Coenzyme Q10
Products Olodaterol was approved in many countries in 2014 as a solution for inhalation (Striverdi). In 2016, a fixed-dose combination with tiotropium bromide was also marketed (Spiolto). Both drugs are administered with the Respimat. Respimat The Respimat is a new inhalation device that releases a visible spray, or aerosol. The droplets are fine and move … Olodaterol
Products There are no medicines containing oripavine on the market in many countries. Oripavine is classified as a narcotic and requires an aggravated prescription. Structure and properties Oripavine (C18H19NO3, Mr = 297.3 g/mol) is an opioid that is structurally closely related to thebaine (3-demethylthebaine). Oripavine is an alkaloid and a natural constituent of several poppy … Oripavin
Effects GnRH antagonists are competitive antagonists of GnRH at pituitary receptors, inhibiting the release of LH and FSH. Indications Suppression of premature LH peaks and prevention of premature ovulation in women undergoing assisted reproductive medicine. Prostate cancer in adult men (degarelix). Agents Cetrorelix (Cetrotide) Degarelix (Firmagon) Ganirelix (Orgalutran, out of trade)
Products Agomelatine is commercially available in the form of film-coated tablets (Valdoxan, generic). It was approved in the EU in 2009 and in many countries in 2010. Structure and properties Agomelatine (C15H17NO2, Mr = 243.30 g/mol) exists as a white powder that is practically insoluble in water. It is a naphthalene analog of the epiphyseal … Agomelatine
Products Nesiritide was commercially available in many countries as a powder for the preparation of an infusion solution (Noratak) and had been approved since 2003. Because of a new study of 7141 patients that failed to show a difference between nesiritide and placebo, the product was withdrawn from the market on Dec. 31, 2011 (O’Connor … Nesiritide
Products Dobutamine is commercially available as an infusion solution (Dobutrex). It has been approved in many countries since 1988. Structure and properties Dobutamine (C18H23NO3, Mr = 301.4 g/mol) is present in drugs as racemate and dobutamine hydrochloride, a white crystalline powder that is sparingly soluble in water. Effects ATC C01CA07 Stimulation of β1-adrenergic receptors. Positively … Dobutamine
