Products Omega-3 fatty acids are usually administered in the form of softgels. Oils for oral use are also available. Some foods are rich in omega-3 fatty acids (see below). Structure and properties The most important omega-3 fatty acids include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). They are polyunsaturated and long-chain fatty acids (PUFA: PolyUnsaturated … Omega 3 Fatty Acids Health Benefits
Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine
Cardiac glycosides are drugs that have a positive effect on the beating power of the heart while lowering the heart rate. They are used to treat heart disease. What are cardiac glycosides? Cardiac glycosides are often referred to as digitalis. This name is in reference to the foxglove (digitalis), which contains cardiac glycosides in fairly … Cardiac Glycosides: Effects, Uses & Risks
Products Canrenone is commercially available as an injectable (Soldactone). It has been approved in many countries since 1975. Structure and properties Canrenone (C22H28O3, Mr = 340.5 g/mol) is an active metabolite of spironolactone (aldactone) and, unlike the latter, is soluble in water. Canrenone is present in drugs as potassium canrenoate, the potassium salt of canrenoic … Canrenon
Products Etanercept is commercially available as a solution for injection (Enbrel, biosimilars). It has been approved in many countries since 2000. The biosimilars Benepali and Erlezi were approved in many countries in 2018. Structure and properties Etanercept is a dimeric fusion protein composed of the extracellular ligand-binding domain of TNF receptor-2 and the Fc domain … Etanercept
Products Trimethoprim and sulfamethoxazole are commercially available in tablet and syrup form (Bactrim, generics). The drug has been approved in many countries since 1969. The Bactrim syrup is no longer available, but a generic is available (Nopil syrup). The fixed combination of the two active ingredients is also called cotrimoxazole. Structure and properties Trimethoprim (C14H18N4O3, … Trimethoprim and Sulfamethoxazole
Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions
Antiarrhythmics are drugs used to treat cardiac arrhythmias. They are used primarily for tachycardia, an accelerated heartbeat. For bradycardia, a slowed heart response, a pacemaker is recommended rather than medication with antiarrhythmics. What are antiarrhythmic drugs? Antiarrhythmics are medications used to treat cardiac arrhythmias. These substances are largely manufactured synthetically and do not occur naturally. … Antiarrhythmic Drugs: Effects, Uses & Risks
Products Mesalazine is commercially available as film-coated tablets, enteric-coated sustained-release tablets, granules, sustained-release granules, clysms, and suppositories (e.g., Asacol, Mezavant, Pentasa, Salofalk). It has been approved in many countries since 1984. Structure and properties Mesalazine (C7H7NO3, Mr = 153.1 g/mol) corresponds to 5-aminosalicylic acid (5-ASA). The active ingredient exists as powders or crystals that are … Mesalazine
Products Cilazapril is commercially available in the form of film-coated tablets (Inhibace). Fixed combinations with hydrochlorothiazide are available (Inhibace plus). Cilazapril has been approved in many countries since 1990. Structure and properties Cilazapril (C22H31N3O5, Mr = 417.5 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is a prodrug that … Cilazapril
Flexible dosage By dividing, the fixed dose of tablets can be changed, which increases flexibility. This is because a dose reduction may be necessary for children, for patients with renal insufficiency, for drug interactions, or for altered drug metabolism. Tablets are also divided for economic reasons. For example, the duration of therapy may be doubled … Divisibility of Tablets
Products In many countries, no medicines containing milnacipran are registered. In other countries, film-coated tablets and capsules are available, for example Savella in the United States. Structure and properties Milnacipran (C15H22N2O, Mr = 246.4 g/mol) is present in the drug as milnacipran hydrochloride, a white crystalline powder that is readily soluble in water. It is … Milnacipran
