Products Antipyretics are available in numerous dosage forms. These include, for example, tablets, effervescent tablets, suppositories, juices, and chewable tablets. The name is derived from the technical term pyrexia (fever). The first synthetic agents, such as acetanilide, salicylic acid, and acetylsalicylic acid, were developed in the 19th century. Structure and properties Antipyretics do not have … Antipyretics
Products Hydroxychloroquine is commercially available in the form of film-coated tablets (Plaquenil, auto-generic: Hydroxychloroquine Zentiva). It has been approved in many countries since 1998. Unlike the closely related chloroquine, it is currently on sale. Generic drugs are registered. Structure and properties Hydroxychloroquine (C18H26ClN3O, Mr = 335.9 g/mol) is an aminoquinoline derivative. It is present in … Hydroxychloroquine
Products Erenumab (Aimovig) was the first agent from the group of CGRP inhibitors to be approved in 2018. Fremanezumab (Ajovy) and galcanezumab (Emgality) followed. Structure and properties CGRP inhibitors are humanized or human monoclonal IgG antibodies directed against calcitonin gene-related peptide (CGRP). Low-molecular-weight CGRP receptor antagonists (so-called Gepante) are in clinical development. Some agents have … CGRP Inhibitors
Controlled release from the drug The special design of a drug can be used to achieve delayed, prolonged, continuous, and controlled release of the active ingredient over an extended period of time. This allows the timing, location, and rate of release to be influenced. Galenics Sustained-release drugs include sustained-release tablets, sustained-release capsules, sustained-release granules, and … Retardation
Elimination at the kidney The kidneys, along with the liver, play a central role in the elimination of pharmaceutical agents. They can be filtered at the glomerulus of the nephron, actively secreted at the proximal tubule, and reabsorbed at various tubular segments. In renal insufficiency, these processes are impaired. This may result in a renally … Dose Adjustment in Renal Insufficiency
Single administration Many medications are administered daily over a long period of time, such as agents for high blood pressure or lipid-lowering agents such as statins for disorders of lipid metabolism. However, various drugs also exist for which a single dose, i.e., a single administration, is sufficient. If necessary, it can be repeated after a … Single Dose
Products Bromelain was commercially available in many countries in the form of dragées (Traumanase), and dietary supplements containing pineapple powder are available. Other drugs are approved abroad, for example, Wobenzym and Phlogenzym. Wobenzym is registered in many countries only in the canton of Appenzell Ausserrhoden. Structure and properties Bromelain is the name given to a … Bromelain Effects and Side Effects
Products Triptans are mainly taken in the form of film-coated tablets and melting tablets. Some are also available as subcutaneous injectable solutions and nasal sprays. Suppositories are no longer commercially available in many countries. Sumatriptan (Imigran) was the first agent in this group to be approved in the United States in 1992 and in many … Triptans: Drug Effects, Side Effects, Dosage and Uses
Products Paracetamol is commercially available in the form of tablets, film-coated tablets, melting tablets, effervescent tablets, as granules, drops, syrups, suppositories, soft capsules, and infusion solution, among others (e.g., Acetalgin, Dafalgan, Panadol, and Tylenol). Paracetamol was not approved until the 1950s (Panadol, Tylenol), although it was developed in the 19th century. It has been registered … Paracetamol: Drug Effects, Side Effects, Dosage and Uses
Products Propranolol is approved for the treatment of hemangioma in the form of an oral solution (hemangiol). The drug goes on sale in many countries in November 2014. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. It is a racemate. Effects … Propranolol (Hemangioma)
Symptoms In infants and young children, fever manifests itself as an elevated body temperature that can usually be felt on the skin. Possible accompanying symptoms include lassitude, irritability, loss of appetite, pain, shiny eyes, and red skin. Fever can be both harmless and an expression of a serious illness that can lead to dangerous complications … Fever in Infants and Young Children
Products Albutrepenone acog alfa was approved in many countries and in the EU in 2016 as a powder and solvent for the preparation of a solution for injection for intravenous use (Idelvion). Structure and properties Albutrepenonacog alfa is a recombinant fusion protein consisting of recombinant blood clotting factor IX combined with recombinant albumin. It is … Albutrepenonacog Alfa
