Sibutramine is an amphetamine derivative and serves as an appetite suppressant in its capacity as an indirect stimulator of the sympathetic nervous system. The active ingredient belongs to the group of serotonin–norepinephrine reuptake inhibitors and thus comes close in its mode of action to various antidepressants and the ADHD drug methylphenidate. Drugs containing sibutramine were … Sibutramine: Effects, Uses & Risks
Amfepramone is an indirect alpha-sympathomimetic and is used in Germany as an appetite suppressant. Because of a not inconsiderable potential for abuse, the active ingredient is prescribed only in urgent cases for a short time for the supportive treatment of obesity. What is amfepramone? Because of a not insignificant potential for abuse, the drug is … Amfepramone: Effects, Uses & Risks
Amifostine, also known as Amifostinum or Amifostinum trihydricum, with trade name Ethyol, is a prescription drug with cell-protective effects established since 1995 and used in chemotherapy, radiotherapy, and prevention of dry mouth. For example, amifostine is used in advanced tumors of the ovaries or head and neck region by limiting potential tissue damage caused by … Amifostine: Effects, Uses & Risks
Kalisaya represents one of 23 species of the plant genus Cinchona (cinchona trees). It was originally native only to South America, where it was used by indigenous people as a medicinal plant against malaria. Today, cinchona trees play a major role only for cinchona production. Occurrence and cultivation of the Kalisaya Kalisaya can grow very … Kalisaya: Applications, Treatments, Health Benefits
Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Zolpidem is commercially available as film-coated tablets, sustained-release tablets, and effervescent tablets (Stilnox, Stilnox CR, generics, USA: Ambien). It has been approved in many countries since 1990. Structure and properties Zolpidem (C19H21N3O, Mr = 307.39 g/mol) is an imidazopyridine that is structurally distinct from the benzodiazepines. It is present in drugs as zolpidem tartrate, … Zolpidem
Products Ziprasidone is commercially available in capsule form (Zeldox, Geodon, generics) and other forms. It has not yet been registered in many countries. It was first approved in the United States in 2001. Structure and properties Ziprasidone (C21H21ClN4OS, Mr = 412.9 g/mol) is present in the capsules as ziprasidone hydrochloride monohydrate, a white to light … Ziprasidone
Products Ziconotide is commercially available as an infusion solution (Prialt). It has been approved in many countries since 2006. Structure and properties Ziconotide (C102H172N36O32S7, Mr = 2639 g/mol) is a peptide of 25 amino acids with three disulfide bridges. It is a synthetic analog of the ω-conopeptide MVIIA, which occurs in the venom of the … Ziconotide
Fenofibrate is, among other fibrates, a variation of clofibric acid. Thereby, it belongs to the lipid-lowering agents like nicotinic acids as well as statins. An increased level of triglycerides is the main spectrum of action of fenofibrate. A cholesterol-lowering effect is less characteristic here, but still present. What is fenofibrate? Fenofibrate (chemical name: 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic acid … Fenofibrate: Effects, Uses & Risks
Products Oxazepam is commercially available in tablet form (Seresta, Anxiolit). It has been approved in many countries since 1966. Structure and properties Oxazepam (C15H11ClN2O2, Mr = 286.7 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. Effects Oxazepam (ATC N05BA04) has antianxiety, sedative, sleep-inducing, anticonvulsant, and muscle … Oxazepam: Drug Effects, Side Effects, Dosage and Uses
Products Oxcarbazepine is available in the form of film-coated tablets, sustained-release tablets, and as a suspension and commercially (Trileptal, Apydan extent). It has been approved in many countries since 1997. Structure and properties Oxcarbazepine (C15H12N2O2, Mr = 252.3 g/mol) exists as a white to faint orange crystalline powder and is practically insoluble in water. Oxcarbazepine … Oxcarbazepine
Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan