Products Dimetinden maleate has been commercially available in many countries since 1974 in the form of a gel (Fenistil Gel). Structure and properties Dimetindene (C20H24N2, Mr = 292.4 g/mol) is present in drugs as dimetindene maleate, a white crystalline powder that is poorly soluble in water. The name is derived from the two methyl groups … Dimetinden Maleate Gel
Products Hydrocortisone butyrate is commercially available as emulsion and cream (Locoid). It has been approved in many countries since 1973. Structure and properties Hydrocortisone-17-butyrate (C25H36O6, Mr = 432.6 g/mol) is an esterified, nonhalogenated glucocorticoid. It is a derivative of endogenous hydrocortisone. Effects Hydrocortisone butyrate (ATC D07AB02) has anti-inflammatory, antiallergic, immunosuppressive, and antipruritic properties. The effects … Hydrocortisone Butyrate
Products Calcipotriol is commercially available as a fixed combination with betamethasone dipropionate as a gel, ointment, and foam (Xamiol, Daivobet, Enstilar, generics). Structure and properties Calcipotriol (C27H40O3, Mr = 412.60 g/mol) is a synthetic derivative of natural vitamin D3 (cholecalciferol). It exists as a white crystalline powder. Effects Calcipotriol (ATC D05AX02) has antiproliferative, anti-inflammatory, and … Calcipotriol
Products Scabi-med cream containing 5% permethrin was approved in many countries in 2018. For the years prior to that, no finished drug product was registered for the treatment of scabies in many countries following the cessation of sales of Eurax (crotamiton). In other countries, however, the cream had been available for years or even decades. … Permethrin Cream
Products Sorafenib is commercially available in the form of film-coated tablets (Nexavar). It has been approved in many countries since 2006. Structure and properties Sorafenib (C21H16ClF3N4O3, Mr = 464.8 g/mol) is present in drugs as sorafenibtosilate, a white to yellowish or brownish powder that is practically insoluble in water. Effects Sorafenib (ATC L01XE05) has antiproliferative, … Sorafenib
Products Hand disinfectant gels are available, for example, in pharmacies and drugstores. Structure and properties Hand disinfectant gels are gelled liquids (gels) for external application on the hands, which contain one or more disinfectants. Typical ingredients are: Disinfectants such as ethanol, propanol and isopropanol (propan-1-ol, propan-2-ol). Purified water Gel formers such as celluloses and carbomers. … Hand Disinfectant Gels
Products Isotretinoin is commercially available in capsule and gel form (Roaccutane, generics). It has been approved in many countries since 1983 (United States: 1982, Accutane). This article refers to the capsules. See also under isotretinoin gel. Structure and properties Isotretinoin (C20H28O2, Mr = 300.4 g/mol) exists as a yellow to light orange crystalline powder that … Isotretinoin
Products Isotretinoin gel has been approved in many countries since 1994 (Roaccutan Gel, Germany: Isotrex Gel). Structure and properties Isotretinoin (C20H28O2, Mr = 300.4 g/mol) exists as a yellow to faint orange crystalline powder that is practically insoluble in water. Especially in solution, it is sensitive to air, heat, and light. Isotretinoin is a stereoisomer … Isotretinoin Gel
Products Pure petrolatum is available in pharmacies and drugstores. It is contained in numerous body care products and cosmetics. In German, the substance may be referred to as “die Vaseline” or “das Vaselin”. In English, Vaseline is a brand name and the substance is called petroleum jelly. The name Vaseline comes from the American Robert … Vaseline: Drug Effects, Side Effects, Dosage and Uses
Symptoms Nummular eczema (from Latin , coin) is an inflammatory skin disease that manifests itself in sharply defined, coin-shaped rashes that primarily affect the extensor sides of the legs, arms, and trunk. The areas are weeping, inflamed (reddened), and may become dry, crusted, and itchy. Unlike cutaneous fungus, the lesions are filled in and do … Nummular Eczema
Symptoms Irritant contact dermatitis is a common inflammatory condition of the skin. It often occurs on the hands and manifests in the following possible signs and symptoms: Redness Swellings Dry skin Scaling, often between the fingers Itching, burning, pain, tightness, tingling. Increased sensitivity, for example, to alcohol in disinfectants. Skin thickening Painful tears Crusts Erosions … Irritant Contact Dermatitis
Products Naftifine is commercially available as a gel and cream for external use. The drug has not yet been registered in many countries. Structure and properties Naftifine (C21H21N, Mr = 287.4 g/mol) is a lipophilic naphthalene derivative and belongs to the group of allylamines, which includes terbinafine. In pharmaceuticals, it is present as naftifine hydrochloride. … Naftifine
