Athlete’s Foot

Symptoms Athlete’s foot (tinea pedis) usually develops between the toes and manifests as sometimes severe itching, burning, reddening of the skin, white softened, peeling and torn skin, skin blisters and dry skin. The symptoms also occur on the soles of the feet and are accompanied by hyperkeratosis. In the course, a difficult-to-treat nail fungus may … Athlete’s Foot

Vaginal Cream: Effect, Uses & Risks

Vaginal creams are used in women in the initm area. There are different areas in which they are used: vaginal inflammation (bacterial vaginosis), fungal infection (mycosis) of the female genitals, vaginal dryness or to prevent inflammatory diseases or infections in the intimate area. What is vaginal cream? Vaginal cream can be used to combat various … Vaginal Cream: Effect, Uses & Risks

Diaper Rash: Symptoms, Causes, Treatment

Symptoms Inflammatory reactions in the diaper area: Reddened, wet, scaly erosions. Often shiny surface Vesicles and pustules Itching Painful open skin Diaper dermatitis with candida infection: Sharply demarcated, moist shiny skin redness in the folds of the buttocks and genital area. Scaly fringe at the transition zones to the healthy skin. Scattering of pinhead-sized nodules … Diaper Rash: Symptoms, Causes, Treatment

Vaginal Suppositories

Products Vaginal suppositories are commercially available as drugs and medical devices. Listed below are some active ingredients which are administered vaginally: Estrogens: estriol Progestins: progesterone Antifungals: Econazole, ciclopirox Antiparasitics: Metronidazole, Clindamycin Antiseptics: Povidone–iodine, formerly boric acid. Probiotics: Lactobacilli The egg-shaped vaginal suppositories are also called ovules (singular ovulum). Structure and properties Vaginal suppositories are dosage … Vaginal Suppositories

Vaginal Fungus

Symptoms Acute, uncomplicated vaginal mycosis occurs more frequently in women of childbearing age. In contrast, it is rare in girls and postmenopausal women. About 75% of all women contract vaginal mycosis once in their lives. The clinical manifestation varies. Possible symptoms include: Itching and burning (leading symptoms). Inflammation of the vagina and vulva with symptoms … Vaginal Fungus

Isoconazole

Products Isoconazole is commercially available as a cream (Travogen, Travocort + diflucortolone valerate). It has been approved in many countries since 1980. The ovules are out of commerce. Structure and properties Isoconazole (C18H14Cl4N2O, Mr = 416.1 g/mol) is present in drugs as a racemate and as isoconazole nitrate, a white powder that is very sparingly … Isoconazole

Antifungals

Products Antifungal products are commercially available as creams, ointments, powders, solutions, tablets, capsules, and injectables, among others. Structure and properties The antifungal agents are a structurally heterogeneous class of agents. However, several groups can be identified within the antifungals, such as the azole antifungals and the allylamines (see below). Effects Antifungals have antifungal, fungistatic, or … Antifungals

Triamcinolone Acetonide

Products Triamcinolone acetonide is commercially available as suspension for injection (Kenacort-A), solution for injection (Kenacort-A Solubile, Ledermix), crystal suspension (Triamcort Depot), paste (Kenacort-A Orabase), tincture (Kenacort-A + salicylic acid), nasal spray (Nasacort, Nasacort Allergo), cream (Pevisone + Econazole). Structure and properties Triamcinolone acetonide (C24H31FO6, Mr = 434.5 g/mol) is a white crystalline powder that is … Triamcinolone Acetonide

Azole Antifungals

Products Azole antifungals are approved in many countries for both topical and systemic treatment. They are available in numerous dosage forms-including creams, an oral gel, powders, sprays, tablets, capsules, injectables, vaginal creams, and vaginal tablets. The first azole antifungal came on the market in the 1950s. Structure and properties The name azole refers to heterocycles … Azole Antifungals

Intertrigo

Symptoms Intertrigo (Latin for “rubbed sore”) is a common inflammatory skin condition that occurs on opposite skin surfaces in skin folds. It is initially manifested by a mild to severe redness that is approximately mirror image on both sides of the skin fold. It is often accompanied by itching, rash, burning sensation and pain. Papules … Intertrigo

Econazole

Products Econazole is commercially available as a cream, powder, pump spray, vaginal cream, and vaginal suppository (Pevaryl, Gyno-Pevaryl, Pevisone + triamcinolone acetonide). The active ingredient has been approved in many countries since 1974. Structure and properties The imidazole derivative econazole (C18H15Cl3N2O, Mr = 381.7 g/mol) is a white powder that is practically insoluble in water. … Econazole