Basilar impression is a pathological abnormality in the area of the cervical vertebrae. The abnormality is seen in the transitional craniocervical region, with an impression developing on the second vertebra of the neck. In particular, the dens axis is affected. Because the basilar impression occurs near the foramen magnum, the condition narrows this segment. What … Basilar Impression: Causes, Symptoms & Treatment
Hydroxylysine is a nonclassical proteinogenic amino acid. It is incorporated into the corresponding protein as lysine and hydrolyzed to hydroxylysine within the polypeptide with the help of an enzyme. It represents one of the main components of collagen proteins of connective tissue. What is hydroxylysine? Hydroxylysine is a proteinogenic amino acid that is first incorporated … Hydroxylysine: Function & Diseases
Keratoconus is a progressive thinning and deformation of the cornea of the eye (cornea). A cone-shaped protrusion of the cornea takes place. Keratoconus is often accompanied by other diseases and, in some cases, genetic disorders. What is keratoconus? Keratoconus is characterized by the cone-shaped deformation and thinning of the cornea of the eye. Both eyes … Keratoconus: Causes, Symptoms & Treatment
Connective tissue weakness manifests itself in various, visually more or less visible impairments of a normal and attractive skin appearance. Connective tissue weakness can occur at a young age or only at an advanced age. What is connective tissue weakness? Schematic diagram showing the anatomy and structure of the skin with and without cellulite. Click … Weakness of Connective Tissue: Causes, Symptoms & Treatment
Hypermobility syndrome (HMS) is characterized by excessive flexibility of the joints caused by congenital connective tissue weakness. Little is known about the cause of the condition. Quality of life is particularly limited by chronic pain in the joints. What is hypermobility syndrome? Hypermobility syndrome is a connective tissue weakness that leads to unusual overmovement of … Hypermobility Syndrome: Causes, Symptoms & Treatment
Drooping eye skin or eyelids filled with fat are not only a visual problem, but can also obstruct vision. We are talking about dermatochalasis, which can occur due to a disease or also due to family history. In almost all cases, the affected person must be treated surgically. What is dermatochalasis? Under a dermatochalasis, the … Dermatochalasis: Causes, Symptoms & Treatment
Wrinkles on the neck are fortunately not a pathological phenomenon, but are perceived as unaesthetic and may still bother those affected very much. With increasing age, wrinkles spread all over the body, and the neck is just as susceptible as the face. How strong wrinkles appear depends on the predisposition, but also the personal lifestyle. … Wrinkles on the Neck: Causes, Treatment & Help
Lysylhydroxylases represent a group of enzymes responsible for the hydroxylation of lysine residues within proteins. Thus, they mainly participate in the formation of connective tissue. Disturbances in the function of lysylhydroxylases manifest themselves in such diseases as scurvy or hereditary Ehlers-Danlos syndrome. What are lysylhydroxylases? Lysylhydroxylases are enzymes whose function is to catalyze the posttranslational … Lysylhydroxylases: Function & Diseases
Splicing represents a crucial process during transcription in the nucleus of eukaryotes, in which mature mRNA emerges from pre-mRNA. In this process, introns that are still present in the pre-mRNA after transcription are removed, and the remaining exons are combined to form the final mRNA. What is splicing? The first step in gene expression is … Splicing: Function, Tasks, Role & Diseases
Acrogeria is also known as Gottron syndrome and is characterized by a complex of predominantly dermal symptoms including atrophy and telangiectasia. The disease is based on a mutation in gene COL3A1, which interferes with the biosynthesis of type III collagen. Therapy to date has been purely symptomatic. What is acrogeria? The disease is apparently one … Acrogeria: Causes, Symptoms & Treatment
Cutis-laxa syndrome is a complex of skin disorders that can be both hereditary and acquired and are associated with wrinkled and wrinkled skin. The clinical pictures are completely different. Only the hereditary cutis laxa disorders will be described below. What is cutis laxa syndrome? Cutis laxa syndrome characterizes a variety of conditions involving wrinkled and … Cutis Laxa Syndrome: Causes, Symptoms & Treatment
Ehlers-Danlos syndrome, also known as EDS, is a connective tissue disorder that is inherited as part of a genetic defect. Above all, EDS is manifested by overly mobile joints as well as overstretchability of the skin. Sometimes vessels, ligaments, muscles as well as tendons and internal organs can also be affected by EDS; the prognosis … Ehlers-Danlos Syndrome: Causes, Symptoms & Treatment