Products Ergocalciferol (vitamin D2, calciferol) is commercially available in many countries, including as a dietary supplement in the form of capsules. Vitamin D2 is much less commonly used than cholecalciferol (vitamin D3) in many countries. In the United States, on the other hand, ergocalciferol is more traditionally used. Structure and properties Ergocalciferol (C28H44O, Mr = … Ergocalciferol (Vitamin D2)
Products Efinaconazole is commercially available in the United States in the form of a solution (Jublia). The active ingredient has not yet been registered in many countries. Structure and properties Efinaconazole (C18H22F2N4O, Mr = 348.4 g/mol) structurally belongs to the triazole antifungals. Effects Efinaconazole has antifungal properties. The effects are due to inhibition of lanosterol … Efinaconazole
Products Ketoconazole has been approved in many countries since 1981 and is now only commercially available as a shampoo and as a cream for external treatment (Nizoral, generics). Nizoral tablets were taken off the market in 2012 due to declining demand. This article refers to external use. Structure and properties Ketoconazole (C26H28Cl2N4O4, Mr = 531.4 … Ketoconazole
Products Itraconazole is commercially available in capsule form and as an oral solution (Sporanox, generic). It has been approved in many countries since 1992. Sporanox infusion concentrate is no longer available. Structure and properties Itraconazole (C35H38Cl2N8O4, Mr = 705.6 g/mol) exists as a white powder that is practically insoluble in water. It belongs to the … Itraconazole
Products Isavuconazonium sulfate is commercially available as a powder for a concentrate for the preparation of an infusion solution and in capsule form (Cresemba). It was approved in the US and EU in 2015 and in many countries in 2017. Structure and properties Isavuconazonium sulfate (C35H35F2N8O5S+ – HSO4– Mr = 814.8 g/mol) is a prodrug … Isavuconazonium Sulfate
Products Isoconazole is commercially available as a cream (Travogen, Travocort + diflucortolone valerate). It has been approved in many countries since 1980. The ovules are out of commerce. Structure and properties Isoconazole (C18H14Cl4N2O, Mr = 416.1 g/mol) is present in drugs as a racemate and as isoconazole nitrate, a white powder that is very sparingly … Isoconazole
Products Naftifine is commercially available as a gel and cream for external use. The drug has not yet been registered in many countries. Structure and properties Naftifine (C21H21N, Mr = 287.4 g/mol) is a lipophilic naphthalene derivative and belongs to the group of allylamines, which includes terbinafine. In pharmaceuticals, it is present as naftifine hydrochloride. … Naftifine
Products In 2009, a water-soluble varnish containing 8% ciclopirox was approved in many countries for the treatment of nail fungus, which is applied once daily (Ciclopoli). It went on sale in January 2011. In many countries, ciclopirox 8% had already been approved for the treatment of nail fungus for a number of years, in France … Ciclopirox against Nail Fungus
Products Azole antifungals are approved in many countries for both topical and systemic treatment. They are available in numerous dosage forms-including creams, an oral gel, powders, sprays, tablets, capsules, injectables, vaginal creams, and vaginal tablets. The first azole antifungal came on the market in the 1950s. Structure and properties The name azole refers to heterocycles … Azole Antifungals
Mushroom , Clavicipitaceae (Ascomycetes) – Tibetan caterpillar club fungus. Life cycle The fungus has a very particular life cycle. Spores infect larvae of certain moths (bat moth , ) in autumn. In spring, the fruiting body of the fungus grows out of the head of the infested caterpillar. Drug Traditionally, the combination of insect and … Tibetan Caterpillar Club Fungus
Products Luliconazole is commercially available as a cream (Luzu). It was registered in the United States in 2013. The drug is not currently approved in many countries. In Japan, luliconazole has been on the market since 2005. Structure and properties Luliconazole (C14H9Cl2N3S2, Mr = 354.3 g/mol) is a chlorinated imidazole and 1,3-dithiolane derivative. Effects Luliconazole … Luliconazole
Products Pentamycin was commercially available in the form of vaginal tablets. It was approved in many countries in 1980 (FemiFect, formerly Pruri-ex). Structure and properties Pentamycin (C35H58O12, Mr = 670.8 g/mol) is a polyene antibiotic isolated from. Effects Pentamycin (ATC G01AA11) has antifungal, antibacterial, and antiparasitic properties. In fungi, the effects are due to binding … Pentamycin