Zinc Oxide

Products Zinc oxide is contained in zinc ointments, shaking mixtures, in sunscreens, skin care products, hemorrhoid ointments, baby care products, cosmetics and wound healing ointments, among others. Zinc oxide is also combined with other active ingredients in a fixed manner and traditionally numerous magistral formulations have been made with the active ingredient. Its medicinal use … Zinc Oxide

Zinc Sulfate

Products Zinc sulfate is commercially available as a gel for the treatment of cold sores (Lipactin, D: Virudermin). It is also sold as a proprietary preparation in some pharmacies (Zinci sulfatis hydrogel 0.1% FH). Hima Pasta is no longer available in many countries. Structure and properties Zinc sulfate is the zinc salt of sulfuric acid. … Zinc Sulfate

Zipeprol

Products Medicines containing zipeprol are no longer on the market in many countries. Mirsol is no longer available. Zipeprol is classified as a narcotic. Structure and properties Zipeprol (C23H32N2O3, Mr = 384.5 g/mol) is a disubstituted piperazine derivative with a non-opioid structure. Effects Zipeprol (ATC R05DB15) has antitussive properties. In addition, anticholinergic, antihistamine, local anesthetic, … Zipeprol

Oxibendazole

Products Oxibendazole is commercially available as an oral paste (Equitac). It has been approved in many countries since 1988. Structure and properties Oxibendazole (C12H15N3O3, Mr = 249.3 g/mol) is a benzimidazole derivative. Effects Oxibendazole (ATCvet QP52AC07) is antihelminthic. Indications For treatment of worm infestation in horses and ponies (nematodes, ).

Rivipansel (GMI-1070)

Products Rivipansel is currently in clinical development at GlycoMimetics and Pfizer. The drug is not yet commercially available. Structure and properties Rivipansel (C58H74N6O31S3, Mr = 1447.4 g/mol) is a glycomimetic developed by the research group led by Prof. Beat Ernst at the Institute of Molecular Pharmacy, University of Basel, in collaboration with GlycoMimetics. Effects Rivipansel … Rivipansel (GMI-1070)

Dihydroartemisinin

Products No drugs containing dihydroartemisinin are currently approved in many countries. However, the prodrug artemether (Riamet, with lumefantrine), which is metabolized in the body to dihydroartemisinin, is available. It is also combined fixed with piperaquine; see Piperaquine and Dihydroartemisinin. Structure and properties Dihydroartemisinin (C15H24O5, Mr = 284.3 g/mol) is derived from artemisinin from annual mugwort … Dihydroartemisinin

Diltiazem

Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem

Quinapril

Products Quinapril is commercially available in the form of film-coated tablets as a monopreparation (Accupro) and as a fixed combination with hydrochlorothiazide (Accuretic, Quiril comp). It has been approved in many countries since 1989. Generic versions are registered. Structure and properties Quinapril (C25H30N2O5, Mr = 438.5 g/mol) is present in drugs as quinapril hydrochloride, a … Quinapril

Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Jellyfish Repellent

Background The skin of jellyfish contains so-called cnidocytes, which are used against prey and enemies when they come into contact with the skin. When appropriately irritated, a cnidocyst is ejected at high speed like a kind of harpoon, injecting a venom deep into the victim’s skin. This venom causes mild to fatal toxic and allergic … Jellyfish Repellent

Misuse of Cough Syrup

Cough syrup as an intoxicant Many antirritant cough syrups contain active ingredients that are psychoactive in high doses and can be abused as intoxicants. Substances include, for example: Opioids such as codeine, dihydrocodeine and ethylmorphine. NMDA antagonists: dextromethorphan Antihistamines such as diphenhydramine and oxomemazine. Phenothiazines: promethazine (out of commerce). Such drugs are unlike other drugs … Misuse of Cough Syrup